E-ISSN 2218-6050 | ISSN 2226-4485
 

Original Article


Alterations of selected serum biochemical and urinary parameters in dogs with chronic enteropathy

Eleonora Gori, Ilaria Lippi, Giulia Ansaldo, Paola Gianella, Francesca Perondi, Alessio Pierini, Veronica Marchetti.


Abstract
Background: no specific study on concurrent nephropathy has been conducted in dogs with chronic enteropathy (CE), except for soft coated wheaten terriers. Moreover, limited information exists regarding urinary profile in dogs with CE.
Aim: to describe, compare, and discuss the alterations in selected serum biochemical and urinary parameters in dogs with CE.
Methods: multicentric retrospective study on dogs with CE diagnosed after exclusion of extra-gastrointestinal diseases. In addition, dogs with azotemia and lower urinary tract diseases were excluded. Information on Canine Chronic Enteropathy Activity Index Score (CCECAI), muscular condition score (MCS), presence of glycosuria, proteinuria [urine protein-to-creatinine (UPC) ratio>0.5], and/or cylindruria (>1-2 casts/hpf) at diagnosis were gleaned from the medical records. Dogs were retrospectively classified as food-responsive enteropathy (FRE), immunosuppressant-responsive enteropathy (IRE) or non-responsive enteropathy (NRE) based on the presence of gastrointestinal histological inflammation and the treatment response. In addition, based on serum albumin concentration, dogs were classified as having protein-losing enteropathy.
Results: ninety CE dogs were included. Fifty-two dogs had mildly-to-severely decreased MCS and 38 dogs showed altered urinary parameters. No significant associations were found between CCECAI and altered urinary parameters. No significant association was found between PLE dogs and altered urinary parameters. PLE dogs showed higher prevalence of proteinuria than non-PLE dogs (p=0.03 OR 2.8 95%CI 1-6.8).
Conclusion: despite the presence of altered urinary profile in dogs with CE, further studies are needed to explore a possible link between gastrointestinal and renal inflammation.

Key words: dog; intestinal disease; urine; proteinuria


 
ARTICLE TOOLS
Abstract
PDF Fulltext
HTML Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Eleonora Gori
Articles by Ilaria Lippi
Articles by Giulia Ansaldo
Articles by Paola Gianella
Articles by Francesca Perondi
Articles by Alessio Pierini
Articles by Veronica Marchetti
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Gori E, Lippi I, Ansaldo G, Gianella P, Perondi F, Pierini A, Marchetti V, . Alterations of selected serum biochemical and urinary parameters in dogs with chronic enteropathy. Open Vet J. 2022; 12(4): 578-583. doi:10.5455/OVJ.2022.v12.i4.21


Web Style

Gori E, Lippi I, Ansaldo G, Gianella P, Perondi F, Pierini A, Marchetti V, . Alterations of selected serum biochemical and urinary parameters in dogs with chronic enteropathy. https://www.openveterinaryjournal.com/?mno=11459 [Access: June 23, 2024]. doi:10.5455/OVJ.2022.v12.i4.21


AMA (American Medical Association) Style

Gori E, Lippi I, Ansaldo G, Gianella P, Perondi F, Pierini A, Marchetti V, . Alterations of selected serum biochemical and urinary parameters in dogs with chronic enteropathy. Open Vet J. 2022; 12(4): 578-583. doi:10.5455/OVJ.2022.v12.i4.21



Vancouver/ICMJE Style

Gori E, Lippi I, Ansaldo G, Gianella P, Perondi F, Pierini A, Marchetti V, . Alterations of selected serum biochemical and urinary parameters in dogs with chronic enteropathy. Open Vet J. (2022), [cited June 23, 2024]; 12(4): 578-583. doi:10.5455/OVJ.2022.v12.i4.21



Harvard Style

Gori, E., Lippi, I., Ansaldo, G., Gianella, P., Perondi, F., Pierini, A., Marchetti, V. & (2022) Alterations of selected serum biochemical and urinary parameters in dogs with chronic enteropathy. Open Vet J, 12 (4), 578-583. doi:10.5455/OVJ.2022.v12.i4.21



Turabian Style

Gori, Eleonora, Ilaria Lippi, Giulia Ansaldo, Paola Gianella, Francesca Perondi, Alessio Pierini, Veronica Marchetti, and . 2022. Alterations of selected serum biochemical and urinary parameters in dogs with chronic enteropathy. Open Veterinary Journal, 12 (4), 578-583. doi:10.5455/OVJ.2022.v12.i4.21



Chicago Style

Gori, Eleonora, Ilaria Lippi, Giulia Ansaldo, Paola Gianella, Francesca Perondi, Alessio Pierini, Veronica Marchetti, and . "Alterations of selected serum biochemical and urinary parameters in dogs with chronic enteropathy." Open Veterinary Journal 12 (2022), 578-583. doi:10.5455/OVJ.2022.v12.i4.21



MLA (The Modern Language Association) Style

Gori, Eleonora, Ilaria Lippi, Giulia Ansaldo, Paola Gianella, Francesca Perondi, Alessio Pierini, Veronica Marchetti, and . "Alterations of selected serum biochemical and urinary parameters in dogs with chronic enteropathy." Open Veterinary Journal 12.4 (2022), 578-583. Print. doi:10.5455/OVJ.2022.v12.i4.21



APA (American Psychological Association) Style

Gori, E., Lippi, I., Ansaldo, G., Gianella, P., Perondi, F., Pierini, A., Marchetti, V. & (2022) Alterations of selected serum biochemical and urinary parameters in dogs with chronic enteropathy. Open Veterinary Journal, 12 (4), 578-583. doi:10.5455/OVJ.2022.v12.i4.21