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2024, Vol: 14, Issue: 11
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Original Article


Long-term supplementation with an undenatured type-II collagen (UC-II®) formulation in dogs with degenerative joint disease: exploratory study

Miguel Angel Cabezas, Javier Benito, Alvaro Ortega, Elena Garcia-Pedraza.


Cited By:6

Abstract
Background: undenatured type II collagen (UC-II®) have demonstrated its benefits in degenerative joint disease (DJD) management. Objective: exploratory clinical study to investigate the beneficial effects of, FLEXADIN-Advanced® in dogs. Methods: multicentre clinical prospective study, 110 client-owned dogs with a clinical diagnosis of DJD. Dogs received FLEXADIN-Advanced® during 6 months. Pain, overall general condition, appetite, mobility and lameness was assessed monthly by veterinarians and owners for 6 months. Compliance as was assessed at 3 and 6 months. Statistical analysis was performed with non-parametric tests (significance, p< 0.05). Results: parameters assessed were significantly lower comparing inclusion with at all subsequent months (P < 0.0001). Compliance at 3 months showed a good score but was significantly lower (P < 0.0001) at six months. Conclusion, FLEXADIN-Advanced®, containing UC-II®, can be considered a good complementary feed to provide joint support in dogs with mild to moderate DJD.

Key words: UC-II; dog; degenerative joint disease; supplement; compliance


 
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How to Cite this Article
Pubmed Style

MAC, Benito J, Ortega A, Garcia-Pedraza E. Long-term supplementation with an undenatured type-II collagen (UC-II®) formulation in dogs with degenerative joint disease: exploratory study. Open Vet J. 2022; 12(1): 91-98. doi:10.5455/OVJ.2022.v12.i1.11

Web Style

MAC, Benito J, Ortega A, Garcia-Pedraza E. Long-term supplementation with an undenatured type-II collagen (UC-II®) formulation in dogs with degenerative joint disease: exploratory study. https://www.openveterinaryjournal.com/?mno=80854 [Access: December 07, 2024]. doi:10.5455/OVJ.2022.v12.i1.11

AMA (American Medical Association) Style

MAC, Benito J, Ortega A, Garcia-Pedraza E. Long-term supplementation with an undenatured type-II collagen (UC-II®) formulation in dogs with degenerative joint disease: exploratory study. Open Vet J. 2022; 12(1): 91-98. doi:10.5455/OVJ.2022.v12.i1.11


Vancouver/ICMJE Style

MAC, Benito J, Ortega A, Garcia-Pedraza E. Long-term supplementation with an undenatured type-II collagen (UC-II®) formulation in dogs with degenerative joint disease: exploratory study. Open Vet J. (2022), [cited December 07, 2024]; 12(1): 91-98. doi:10.5455/OVJ.2022.v12.i1.11


Harvard Style

, M. A. C., Benito, . J., Ortega, . A. & Garcia-Pedraza, . E. (2022) Long-term supplementation with an undenatured type-II collagen (UC-II®) formulation in dogs with degenerative joint disease: exploratory study. Open Vet J, 12 (1), 91-98. doi:10.5455/OVJ.2022.v12.i1.11


Turabian Style

, Miguel Angel Cabezas, Javier Benito, Alvaro Ortega, and Elena Garcia-Pedraza. 2022. Long-term supplementation with an undenatured type-II collagen (UC-II®) formulation in dogs with degenerative joint disease: exploratory study. Open Veterinary Journal, 12 (1), 91-98. doi:10.5455/OVJ.2022.v12.i1.11


Chicago Style

, Miguel Angel Cabezas, Javier Benito, Alvaro Ortega, and Elena Garcia-Pedraza. "Long-term supplementation with an undenatured type-II collagen (UC-II®) formulation in dogs with degenerative joint disease: exploratory study." Open Veterinary Journal 12 (2022), 91-98. doi:10.5455/OVJ.2022.v12.i1.11


MLA (The Modern Language Association) Style

, Miguel Angel Cabezas, Javier Benito, Alvaro Ortega, and Elena Garcia-Pedraza. "Long-term supplementation with an undenatured type-II collagen (UC-II®) formulation in dogs with degenerative joint disease: exploratory study." Open Veterinary Journal 12.1 (2022), 91-98. Print. doi:10.5455/OVJ.2022.v12.i1.11


APA (American Psychological Association) Style

, M. A. C., Benito, . J., Ortega, . A. & Garcia-Pedraza, . E. (2022) Long-term supplementation with an undenatured type-II collagen (UC-II®) formulation in dogs with degenerative joint disease: exploratory study. Open Veterinary Journal, 12 (1), 91-98. doi:10.5455/OVJ.2022.v12.i1.11


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