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2024, Vol: 14, Issue: 12
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Review Article


African swine fever virus proteins against host antiviral innate immunity and their implications for vaccine development

Fredmoore L. Orosco.


Abstract
African Swine Fever Virus (ASFV) poses a significant threat to global swine populations, necessitating a profound understanding of viral strategies against host antiviral innate immunity. This review synthesizes current knowledge regarding ASFV proteins and their intricate interactions with host defenses. Noteworthy findings encompass the modulation of interferon signaling, manipulation of inflammatory pathways, and the impact on cellular apoptosis. The implications of these findings provide a foundation for advancing vaccine strategies against ASFV. In conclusion, this review consolidates current knowledge, emphasizing the adaptability of ASFV in subverting host immunity. Identified research gaps underscore the need for continued exploration, presenting opportunities for developing targeted vaccines. This synthesis provides a roadmap for future investigations, aiming to enhance our preparedness against the devastating impact of ASFV on global swine populations.

Key words: African swine fever virus, Antiviral innate immune response, Virulence factors, Pathogenicity, Vaccine development


 
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How to Cite this Article
Pubmed Style

Fredmoore L. Orosco. African swine fever virus proteins against host antiviral innate immunity and their implications for vaccine development. Open Vet J. 2024; 14(4): 941-951. doi:10.5455/OVJ.2024.v14.i4.1

Web Style

Fredmoore L. Orosco. African swine fever virus proteins against host antiviral innate immunity and their implications for vaccine development. https://www.openveterinaryjournal.com/?mno=179757 [Access: January 22, 2025]. doi:10.5455/OVJ.2024.v14.i4.1

AMA (American Medical Association) Style

Fredmoore L. Orosco. African swine fever virus proteins against host antiviral innate immunity and their implications for vaccine development. Open Vet J. 2024; 14(4): 941-951. doi:10.5455/OVJ.2024.v14.i4.1


Vancouver/ICMJE Style

Fredmoore L. Orosco. African swine fever virus proteins against host antiviral innate immunity and their implications for vaccine development. Open Vet J. (2024), [cited January 22, 2025]; 14(4): 941-951. doi:10.5455/OVJ.2024.v14.i4.1


Harvard Style

Fredmoore L. Orosco (2024) African swine fever virus proteins against host antiviral innate immunity and their implications for vaccine development. Open Vet J, 14 (4), 941-951. doi:10.5455/OVJ.2024.v14.i4.1


Turabian Style

Fredmoore L. Orosco. 2024. African swine fever virus proteins against host antiviral innate immunity and their implications for vaccine development. Open Veterinary Journal, 14 (4), 941-951. doi:10.5455/OVJ.2024.v14.i4.1


Chicago Style

Fredmoore L. Orosco. "African swine fever virus proteins against host antiviral innate immunity and their implications for vaccine development." Open Veterinary Journal 14 (2024), 941-951. doi:10.5455/OVJ.2024.v14.i4.1


MLA (The Modern Language Association) Style

Fredmoore L. Orosco. "African swine fever virus proteins against host antiviral innate immunity and their implications for vaccine development." Open Veterinary Journal 14.4 (2024), 941-951. Print. doi:10.5455/OVJ.2024.v14.i4.1


APA (American Psychological Association) Style

Fredmoore L. Orosco (2024) African swine fever virus proteins against host antiviral innate immunity and their implications for vaccine development. Open Veterinary Journal, 14 (4), 941-951. doi:10.5455/OVJ.2024.v14.i4.1


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