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2025, Vol: 15, Issue: 6
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Rift Valley fever: A zoonotic disease with global potential

Eka Pramyrtha Hestianah, Aswin Rafif Khairullah, Mustofa Helmi Effendi, Budiastuti Budiastuti, Wiwiek Tyasningsih, Budiarto Budiarto, Dian Ayu Permatasari, Ikechukwu Benjamin Moses, Riza Zainuddin Ahmad, Bantari Wisynu Kusuma Wardhani, Muhammad Khaliim Jati Kusala, Dea Anita Ariani Kurniasih, Ima Fauziah, Syahputra Wibowo, Emmanuel Nnabuike Ugbo, Kartika Afrida Fauzia.


Abstract
An arthropod-borne zoonotic disease called Rift Valley fever (RVF) spreads widely among ruminant animals and humans. Rift Valley Fever is caused by the Rift Valley Fever Virus (RVFV), a round-enveloped RNA virus belonging to the genus Phlebovirus and family Bunyaviridae. RVF is exclusively found in African nations, and it is primarily associated with high rainfall and dense vector mosquito populations. The virus moves from the initial replication site to vital organs such as the brain, liver, and spleen after infection. These organs either recover due to both general and particular host responses, or they are harmed by the pathogenic effects of the virus or immunological pathological processes. The main lesion seen in RVF is hepatic necrosis. The RVFV can be diagnosed in clinical laboratories using a variety of techniques. RVF is defined by high rates of abortion and high newborn death, which typically follow periods of intense precipitation. Commonly observed pathologies include gastrointestinal hemorrhage, splenomegaly, and liver necrosis. Transmission of the virus between Aedes or Culex mosquitoes in flood water has been proven to occur transovarially. A number of ecological, anthropogenic, environmental, and viral evolutionary risk factors combine to make it more likely for RVFV to spread and establish itself in new locations. Although there isn't a specific treatment for human or animal RVF, supportive care can be beneficial. RVF can be prevented in a number of ways, such as by detecting climatic change, controlling mosquito populations, immunizing animals in endemic areas, and managing travel.

Key words: RVF, RVFV, Mosquito, Public health, Virus


 
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How to Cite this Article
Pubmed Style

Hestianah EP, Khairullah AR, Effendi MH, Budiastuti B, Tyasningsih W, Budiarto B, Permatasari DA, Moses IB, Ahmad RZ, Wardhani BWK, Kusala MKJ, Kurniasih DAA, Fauziah I, Wibowo S, Ugbo EN, Fauzia KA. Rift Valley fever: A zoonotic disease with global potential. Open Vet J. 2025; 15(6): 2312-2328. doi:10.5455/OVJ.2025.v15.i6.5

Web Style

Hestianah EP, Khairullah AR, Effendi MH, Budiastuti B, Tyasningsih W, Budiarto B, Permatasari DA, Moses IB, Ahmad RZ, Wardhani BWK, Kusala MKJ, Kurniasih DAA, Fauziah I, Wibowo S, Ugbo EN, Fauzia KA. Rift Valley fever: A zoonotic disease with global potential. https://www.openveterinaryjournal.com/?mno=241293 [Access: July 05, 2025]. doi:10.5455/OVJ.2025.v15.i6.5

AMA (American Medical Association) Style

Hestianah EP, Khairullah AR, Effendi MH, Budiastuti B, Tyasningsih W, Budiarto B, Permatasari DA, Moses IB, Ahmad RZ, Wardhani BWK, Kusala MKJ, Kurniasih DAA, Fauziah I, Wibowo S, Ugbo EN, Fauzia KA. Rift Valley fever: A zoonotic disease with global potential. Open Vet J. 2025; 15(6): 2312-2328. doi:10.5455/OVJ.2025.v15.i6.5


Vancouver/ICMJE Style

Hestianah EP, Khairullah AR, Effendi MH, Budiastuti B, Tyasningsih W, Budiarto B, Permatasari DA, Moses IB, Ahmad RZ, Wardhani BWK, Kusala MKJ, Kurniasih DAA, Fauziah I, Wibowo S, Ugbo EN, Fauzia KA. Rift Valley fever: A zoonotic disease with global potential. Open Vet J. (2025), [cited July 05, 2025]; 15(6): 2312-2328. doi:10.5455/OVJ.2025.v15.i6.5


Harvard Style

Hestianah, E. P., Khairullah, . A. R., Effendi, . M. H., Budiastuti, . B., Tyasningsih, . W., Budiarto, . B., Permatasari, . D. A., Moses, . I. B., Ahmad, . R. Z., Wardhani, . B. W. K., Kusala, . M. K. J., Kurniasih, . D. A. A., Fauziah, . I., Wibowo, . S., Ugbo, . E. N. & Fauzia, . K. A. (2025) Rift Valley fever: A zoonotic disease with global potential. Open Vet J, 15 (6), 2312-2328. doi:10.5455/OVJ.2025.v15.i6.5


Turabian Style

Hestianah, Eka Pramyrtha, Aswin Rafif Khairullah, Mustofa Helmi Effendi, Budiastuti Budiastuti, Wiwiek Tyasningsih, Budiarto Budiarto, Dian Ayu Permatasari, Ikechukwu Benjamin Moses, Riza Zainuddin Ahmad, Bantari Wisynu Kusuma Wardhani, Muhammad Khaliim Jati Kusala, Dea Anita Ariani Kurniasih, Ima Fauziah, Syahputra Wibowo, Emmanuel Nnabuike Ugbo, and Kartika Afrida Fauzia. 2025. Rift Valley fever: A zoonotic disease with global potential. Open Veterinary Journal, 15 (6), 2312-2328. doi:10.5455/OVJ.2025.v15.i6.5


Chicago Style

Hestianah, Eka Pramyrtha, Aswin Rafif Khairullah, Mustofa Helmi Effendi, Budiastuti Budiastuti, Wiwiek Tyasningsih, Budiarto Budiarto, Dian Ayu Permatasari, Ikechukwu Benjamin Moses, Riza Zainuddin Ahmad, Bantari Wisynu Kusuma Wardhani, Muhammad Khaliim Jati Kusala, Dea Anita Ariani Kurniasih, Ima Fauziah, Syahputra Wibowo, Emmanuel Nnabuike Ugbo, and Kartika Afrida Fauzia. "Rift Valley fever: A zoonotic disease with global potential." Open Veterinary Journal 15 (2025), 2312-2328. doi:10.5455/OVJ.2025.v15.i6.5


MLA (The Modern Language Association) Style

Hestianah, Eka Pramyrtha, Aswin Rafif Khairullah, Mustofa Helmi Effendi, Budiastuti Budiastuti, Wiwiek Tyasningsih, Budiarto Budiarto, Dian Ayu Permatasari, Ikechukwu Benjamin Moses, Riza Zainuddin Ahmad, Bantari Wisynu Kusuma Wardhani, Muhammad Khaliim Jati Kusala, Dea Anita Ariani Kurniasih, Ima Fauziah, Syahputra Wibowo, Emmanuel Nnabuike Ugbo, and Kartika Afrida Fauzia. "Rift Valley fever: A zoonotic disease with global potential." Open Veterinary Journal 15.6 (2025), 2312-2328. Print. doi:10.5455/OVJ.2025.v15.i6.5


APA (American Psychological Association) Style

Hestianah, E. P., Khairullah, . A. R., Effendi, . M. H., Budiastuti, . B., Tyasningsih, . W., Budiarto, . B., Permatasari, . D. A., Moses, . I. B., Ahmad, . R. Z., Wardhani, . B. W. K., Kusala, . M. K. J., Kurniasih, . D. A. A., Fauziah, . I., Wibowo, . S., Ugbo, . E. N. & Fauzia, . K. A. (2025) Rift Valley fever: A zoonotic disease with global potential. Open Veterinary Journal, 15 (6), 2312-2328. doi:10.5455/OVJ.2025.v15.i6.5


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