E-ISSN 2218-6050 | ISSN 2226-4485
 

Review Article


Susceptibility of SARS, MERS and COVID-19 from animal health perspective

Aasish Gautam, Samiksha Phuyal, Birendra Shrestha, Krishna Kaphle.


Cited By:45

Abstract
Virus are having great time as they seem to have bogged human down. Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS) and Novel Coronavirus (COVID-19) are the three coronaviruses of present global human and animal health concern. COVID-19 caused by SARS-CoV-2 was identified as a newest disease presumably of bat origin. Different theory of evolution of virus is in circulation, yet there is no denying the fact that animal source is the skeleton. The whole world is witnessing to the terror of COVID-19 pandemic that is following the same path of SARS and MERS. Besides human, several species of animals are reported to have been contaminated with these life threatening viruses. The possible route of transmission, their zoonotic potentialities is a subject of intense research. The review aims to overview the link of all these three deadly coronaviruses among animals along with their phylogenic evolution and cross species transmission. This is essential as animal as pet or food is said to pose some risk and better understanding is a must to prepare possible plan for its future havoc both in human and animal health. Though COVID-19 which is causing widespread human health hazard globally, its reporting in animals are limited compared to SARS and MERS. Non- human primates and carnivores are most susceptible to SARS-coronavirus and SARS-CoV-2 respectively whereas dromedary camel for MERS- coronavirus. Phylogenetically all the trio viruses is reported to have originated from bat and have special capacity to undergo mutation and genomic recombination to infect humans through its reservoir or replication host. It is difficult to analyze how genomic pattern of coronaviruses occur. Thus, increased possibility of more new virus variant generation to infect human and animal in upcoming day seems biggest challenges for future world. One health approach is portrayed as our best way ahead and understanding the animal dimension will go long way in formulating such preparedness plans.

Key words: animal health, trio coronaviruses, COVID-19, cross-species, one health


 
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