E-ISSN 2218-6050 | ISSN 2226-4485
 

Research Article


Experimental trials to assess the immune modulatory influence of thyme and ginseng oil on NDV-vaccinated broiler chickens

Ola Hassanin, Ahmed El- Sebai, Sabry Abd El- Motaal, Hesham A. Khalifa.


Abstract
Background:
The use of traditional medicine against viral disease in animal production has been practiced worldwide. Herbal extracts possess organic substances would improve chicken body performance.
Aim:
The current study was designed to evaluate the effect of either thyme or ginseng oil in regard to their immune-modulatory, antiviral, and growth promoter properties.
Methods:
Two hundred and forty- one -day- old broiler chicks were allocated into eight equal groups as the following: group 1; non-vaccinated and non-treated and group 2; NDV vaccinated and non-treated. Birds of groups 3 and 4 were treated with thyme oil (200mg/L of drinking water for 12 hrs/day) without or with NDV vaccination. Birds of groups 5 and 6 were treated with ginseng oil (200mg/L of drinking water for 12 hrs/day) without or with NDV vaccination. Birds of groups 7 and 8 were treated with a combination of ginseng oil (100mg/L of drinking water) and thyme oil (100mg/L of drinking water) for 12 hrs/day. On the 35th day of life, birds in all the experimental groups were given 0.1 mL of a virulent genotype VIId NDV strain suspension containing 106.3 EID50/mL intramuscularly (IM).
Results:
Administration of ginseng and thyme oils each alone or simultaneously to birds either vaccinated or non-vaccinated elicited a significant improvement in body performance parameters. Administration of thyme and ginseng each alone or concurrently to vaccinated birds (Gp 4, 6 and 8) induced a higher HI titer of 6, 7.3 and 6.3 log2 at 21 days of age, 6.7, 7.6 and 7 log2, at 28 days of age and 7, 8 and 6.8 log2 at 35 days of age, respectively. Challenge with vNDV genotype VII led to an increase in the NDV-specific HI-Ab titers ten days post-challenge in all the experimental groups. In addition, thyme, ginseng oils or a combination of them improved the protection from mortality in vaccinated birds; 100%, 100% and 90% respectively, compared with 80% protection from mortality in vaccinated-only birds post-NDV challenge. Moreover, NDV-vaccinated birds treated either with thyme; ginseng or their combination showed negative detection of the virus in both tracheal and cloacal swabs and non-vaccinated groups that received oils showed improvement in vNDV shedding in tracheal and cloacal swabs.
Conclusion:
It could be concluded that administration of thyme and ginseng essential oils to broilers can improve productive performance parameters, stimulate humoral immunity against, and protect from vNDV infection.

Key words: NDV, Ginseng, Thyme, Chicken, Genotype VII


 
ARTICLE TOOLS
Abstract
PDF Fulltext
HTML Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Ola Hassanin
Articles by Ahmed El- Sebai
Articles by Sabry Abd El- Motaal
Articles by Hesham A. Khalifa
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Hassanin O, Sebai AE, Motaal SAE, Khalifa HA, . Experimental trials to assess the immune modulatory influence of thyme and ginseng oil on NDV-vaccinated broiler chickens. Open Vet J. 2024; 14((1) (Zagazig Veterinary Conference)): 398-406. doi:10.5455/OVJ.2024.v14.i1.36


Web Style

Hassanin O, Sebai AE, Motaal SAE, Khalifa HA, . Experimental trials to assess the immune modulatory influence of thyme and ginseng oil on NDV-vaccinated broiler chickens. https://www.openveterinaryjournal.com/?mno=179264 [Access: April 10, 2024]. doi:10.5455/OVJ.2024.v14.i1.36


AMA (American Medical Association) Style

Hassanin O, Sebai AE, Motaal SAE, Khalifa HA, . Experimental trials to assess the immune modulatory influence of thyme and ginseng oil on NDV-vaccinated broiler chickens. Open Vet J. 2024; 14((1) (Zagazig Veterinary Conference)): 398-406. doi:10.5455/OVJ.2024.v14.i1.36



Vancouver/ICMJE Style

Hassanin O, Sebai AE, Motaal SAE, Khalifa HA, . Experimental trials to assess the immune modulatory influence of thyme and ginseng oil on NDV-vaccinated broiler chickens. Open Vet J. (2024), [cited April 10, 2024]; 14((1) (Zagazig Veterinary Conference)): 398-406. doi:10.5455/OVJ.2024.v14.i1.36



Harvard Style

Hassanin, O., Sebai, A. E., Motaal, S. A. E., Khalifa, H. A. & (2024) Experimental trials to assess the immune modulatory influence of thyme and ginseng oil on NDV-vaccinated broiler chickens. Open Vet J, 14 ((1) (Zagazig Veterinary Conference)), 398-406. doi:10.5455/OVJ.2024.v14.i1.36



Turabian Style

Hassanin, Ola, Ahmed El- Sebai, Sabry Abd El- Motaal, Hesham A. Khalifa, and . 2024. Experimental trials to assess the immune modulatory influence of thyme and ginseng oil on NDV-vaccinated broiler chickens. Open Veterinary Journal, 14 ((1) (Zagazig Veterinary Conference)), 398-406. doi:10.5455/OVJ.2024.v14.i1.36



Chicago Style

Hassanin, Ola, Ahmed El- Sebai, Sabry Abd El- Motaal, Hesham A. Khalifa, and . "Experimental trials to assess the immune modulatory influence of thyme and ginseng oil on NDV-vaccinated broiler chickens." Open Veterinary Journal 14 (2024), 398-406. doi:10.5455/OVJ.2024.v14.i1.36



MLA (The Modern Language Association) Style

Hassanin, Ola, Ahmed El- Sebai, Sabry Abd El- Motaal, Hesham A. Khalifa, and . "Experimental trials to assess the immune modulatory influence of thyme and ginseng oil on NDV-vaccinated broiler chickens." Open Veterinary Journal 14.(1) (Zagazig Veterinary Conference) (2024), 398-406. Print. doi:10.5455/OVJ.2024.v14.i1.36



APA (American Psychological Association) Style

Hassanin, O., Sebai, A. E., Motaal, S. A. E., Khalifa, H. A. & (2024) Experimental trials to assess the immune modulatory influence of thyme and ginseng oil on NDV-vaccinated broiler chickens. Open Veterinary Journal, 14 ((1) (Zagazig Veterinary Conference)), 398-406. doi:10.5455/OVJ.2024.v14.i1.36