E-ISSN 2218-6050 | ISSN 2226-4485
 
2024, Vol: 14, Issue: 11
14 / 11Current Issue ArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles
Required files to be uploaded

OVJ Manuscript Submission Form

Case Report


First report of Cerebellar Abiotrophy in an Arabian Foal from Argentina.

Sebastian Andres Sadaba, Gonzalo Julian Madariaga, Claudia Malena Corbi Botto, Monica Carino, Maria Eugenia Zappa, Silvia Olgin, Pilar Peral Garcia, Adriana Raquel Massone, Silvina Diaz.


Cited By:9

Abstract
Evidence of cerebellar abiotrophy (CA) was found in a six-month-old Arabian filly with signs of incoordination, head tremor, wobbling, loss of balance and falling over, consistent with a cerebellar lesion. Normal hematology profile blood test and cerebrospinal fluid analysis excluded infectious encephalitis, and serological testing for Sarcocystis neurona was negative. The filly was euthanized. Postmortem X-ray radiography of the cervical cephalic region identified not abnormalities, discounting spinal trauma. The histopathological analysis of serial transverse cerebellar sections by electron microscopy revealed morphological characteristics of apoptotic cells with pyknotic nuclei and degenerate mitochondria, cytoplasmic condensation and areas with absence of Purkinje cells, matching with CA histopathological characteristics. The indirect DNA test for CA was positive in the filly, and DNA test confirmed the CA carrier state in the parents and the recessive inheritance of the disease. To our knowledge this is the first report of a CA case in Argentina.

Key words: cerebellar abiotrophy, Arabian horses, DNA, Purkinje cells, apoptosis


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Sebastian Andres Sadaba
Articles by Gonzalo Julian Madariaga
Articles by Claudia Malena Corbi Botto
Articles by Monica Carino
Articles by Maria Eugenia Zappa
Articles by Silvia Olgin
Articles by Pilar Peral Garcia
Articles by Adriana Raquel Massone
Articles by Silvina Diaz
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Sebastian Andres Sadaba, Gonzalo Julian Madariaga, Claudia Malena Corbi Botto, Monica Carino, Maria Eugenia Zappa, Silvia Olgin, Pilar Peral Garcia, Adriana Raquel Massone, Silvina Diaz. First report of Cerebellar Abiotrophy in an Arabian Foal from Argentina.. Open Vet J. 2016; 6(3): 259-262. doi:10.4314/ovj.v6i3.17

Web Style

Sebastian Andres Sadaba, Gonzalo Julian Madariaga, Claudia Malena Corbi Botto, Monica Carino, Maria Eugenia Zappa, Silvia Olgin, Pilar Peral Garcia, Adriana Raquel Massone, Silvina Diaz. First report of Cerebellar Abiotrophy in an Arabian Foal from Argentina.. https://www.openveterinaryjournal.com/?mno=238076 [Access: December 06, 2024]. doi:10.4314/ovj.v6i3.17

AMA (American Medical Association) Style

Sebastian Andres Sadaba, Gonzalo Julian Madariaga, Claudia Malena Corbi Botto, Monica Carino, Maria Eugenia Zappa, Silvia Olgin, Pilar Peral Garcia, Adriana Raquel Massone, Silvina Diaz. First report of Cerebellar Abiotrophy in an Arabian Foal from Argentina.. Open Vet J. 2016; 6(3): 259-262. doi:10.4314/ovj.v6i3.17


Vancouver/ICMJE Style

Sebastian Andres Sadaba, Gonzalo Julian Madariaga, Claudia Malena Corbi Botto, Monica Carino, Maria Eugenia Zappa, Silvia Olgin, Pilar Peral Garcia, Adriana Raquel Massone, Silvina Diaz. First report of Cerebellar Abiotrophy in an Arabian Foal from Argentina.. Open Vet J. (2016), [cited December 06, 2024]; 6(3): 259-262. doi:10.4314/ovj.v6i3.17


Harvard Style

Sebastian Andres Sadaba, Gonzalo Julian Madariaga, Claudia Malena Corbi Botto, Monica Carino, Maria Eugenia Zappa, Silvia Olgin, Pilar Peral Garcia, Adriana Raquel Massone, Silvina Diaz (2016) First report of Cerebellar Abiotrophy in an Arabian Foal from Argentina.. Open Vet J, 6 (3), 259-262. doi:10.4314/ovj.v6i3.17


Turabian Style

Sebastian Andres Sadaba, Gonzalo Julian Madariaga, Claudia Malena Corbi Botto, Monica Carino, Maria Eugenia Zappa, Silvia Olgin, Pilar Peral Garcia, Adriana Raquel Massone, Silvina Diaz. 2016. First report of Cerebellar Abiotrophy in an Arabian Foal from Argentina.. Open Veterinary Journal, 6 (3), 259-262. doi:10.4314/ovj.v6i3.17


Chicago Style

Sebastian Andres Sadaba, Gonzalo Julian Madariaga, Claudia Malena Corbi Botto, Monica Carino, Maria Eugenia Zappa, Silvia Olgin, Pilar Peral Garcia, Adriana Raquel Massone, Silvina Diaz. "First report of Cerebellar Abiotrophy in an Arabian Foal from Argentina.." Open Veterinary Journal 6 (2016), 259-262. doi:10.4314/ovj.v6i3.17


MLA (The Modern Language Association) Style

Sebastian Andres Sadaba, Gonzalo Julian Madariaga, Claudia Malena Corbi Botto, Monica Carino, Maria Eugenia Zappa, Silvia Olgin, Pilar Peral Garcia, Adriana Raquel Massone, Silvina Diaz. "First report of Cerebellar Abiotrophy in an Arabian Foal from Argentina.." Open Veterinary Journal 6.3 (2016), 259-262. Print. doi:10.4314/ovj.v6i3.17


APA (American Psychological Association) Style

Sebastian Andres Sadaba, Gonzalo Julian Madariaga, Claudia Malena Corbi Botto, Monica Carino, Maria Eugenia Zappa, Silvia Olgin, Pilar Peral Garcia, Adriana Raquel Massone, Silvina Diaz (2016) First report of Cerebellar Abiotrophy in an Arabian Foal from Argentina.. Open Veterinary Journal, 6 (3), 259-262. doi:10.4314/ovj.v6i3.17


Author LoginReviewer LoginAbout PublisherPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyTerms of UseLicense InformationCopyright Information

About Open Veterinary Journal

Open Veterinary Journal provides a fast track coupled with high quality peer review process for original research articles, review articles, short communi ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information

All correspondence should be addressed to:

Prof. Ibrahim Eldaghayes: Owner, Founder and Editor-in-Chief

Open Veterinary Journal


Faculty of Veterinary Medicine, University of Tripoli

P.O. Box 13662, Tripoli, Libya

and


Eldaghayes Publisher

www.eldagpublisher.com 

Email: ibrahim.eldaghayes@vetmed.edu.ly