E-ISSN 2218-6050 | ISSN 2226-4485
 
2024, Vol: 14, Issue: 11
14 / 11Current Issue ArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles
Required files to be uploaded

OVJ Manuscript Submission Form

Case Report


MULTIPLE MYELOMA IN AN AMUR TIGER (PANTHERA TIGRIS ALTAICA)

Alison Marie Lee, Naomi Guppy, John Bainbridge, Hanne Jahns.


Cited By:3

Abstract
The Amur tiger (Panthera tigris altaica) is an endangered tiger subspecies. An adult zoo-bred female was found collapsed, and died despite supportive treatment. Hematology and biochemistry showed pancytopenia and hyperglobulinemia, and serum protein electrophoresis revealed a monoclonal band in the β-globulin region. Necropsy demonstrated hemoabdomen, multifocal lytic bone marrow lesions, splenomegaly, and hemorrhagic hepatic nodules, with left medial lobe rupture. There were mutifocal hemorrhages in the subcutis, lung, epicardium, and intestinal mucosa. Histopathology demonstrated plasmacytoid cells infiltrating the bone marrow, liver and spleen, and circulating within blood vessels. On immunohistochemistry, cell infiltrates of the three tissues were positive for λ light chains, bone marrow infiltrates were positive for MUM-1 and bone marrow and spleen infiltrates were positive for CD20. These findings indicate that this animal died of hemoabdomen subsequent to multiple myeloma. This is the first time this disease has been reported in a tiger.

Key words: Amur tiger, immunohistochemistry, multiple myeloma, serum protein electrophoresis, Pantera tigris altaica


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Alison Marie Lee
Articles by Naomi Guppy
Articles by John Bainbridge
Articles by Hanne Jahns
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Alison Marie Lee, Naomi Guppy, John Bainbridge, Hanne Jahns. MULTIPLE MYELOMA IN AN AMUR TIGER (PANTHERA TIGRIS ALTAICA). Open Vet J. 2017; 7(4): 300-305. doi:10.4314/ovj.v7i4.2

Web Style

Alison Marie Lee, Naomi Guppy, John Bainbridge, Hanne Jahns. MULTIPLE MYELOMA IN AN AMUR TIGER (PANTHERA TIGRIS ALTAICA). https://www.openveterinaryjournal.com/?mno=271613 [Access: December 07, 2024]. doi:10.4314/ovj.v7i4.2

AMA (American Medical Association) Style

Alison Marie Lee, Naomi Guppy, John Bainbridge, Hanne Jahns. MULTIPLE MYELOMA IN AN AMUR TIGER (PANTHERA TIGRIS ALTAICA). Open Vet J. 2017; 7(4): 300-305. doi:10.4314/ovj.v7i4.2


Vancouver/ICMJE Style

Alison Marie Lee, Naomi Guppy, John Bainbridge, Hanne Jahns. MULTIPLE MYELOMA IN AN AMUR TIGER (PANTHERA TIGRIS ALTAICA). Open Vet J. (2017), [cited December 07, 2024]; 7(4): 300-305. doi:10.4314/ovj.v7i4.2


Harvard Style

Alison Marie Lee, Naomi Guppy, John Bainbridge, Hanne Jahns (2017) MULTIPLE MYELOMA IN AN AMUR TIGER (PANTHERA TIGRIS ALTAICA). Open Vet J, 7 (4), 300-305. doi:10.4314/ovj.v7i4.2


Turabian Style

Alison Marie Lee, Naomi Guppy, John Bainbridge, Hanne Jahns. 2017. MULTIPLE MYELOMA IN AN AMUR TIGER (PANTHERA TIGRIS ALTAICA). Open Veterinary Journal, 7 (4), 300-305. doi:10.4314/ovj.v7i4.2


Chicago Style

Alison Marie Lee, Naomi Guppy, John Bainbridge, Hanne Jahns. "MULTIPLE MYELOMA IN AN AMUR TIGER (PANTHERA TIGRIS ALTAICA)." Open Veterinary Journal 7 (2017), 300-305. doi:10.4314/ovj.v7i4.2


MLA (The Modern Language Association) Style

Alison Marie Lee, Naomi Guppy, John Bainbridge, Hanne Jahns. "MULTIPLE MYELOMA IN AN AMUR TIGER (PANTHERA TIGRIS ALTAICA)." Open Veterinary Journal 7.4 (2017), 300-305. Print. doi:10.4314/ovj.v7i4.2


APA (American Psychological Association) Style

Alison Marie Lee, Naomi Guppy, John Bainbridge, Hanne Jahns (2017) MULTIPLE MYELOMA IN AN AMUR TIGER (PANTHERA TIGRIS ALTAICA). Open Veterinary Journal, 7 (4), 300-305. doi:10.4314/ovj.v7i4.2


Author LoginReviewer LoginAbout PublisherPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyTerms of UseLicense InformationCopyright Information

About Open Veterinary Journal

Open Veterinary Journal provides a fast track coupled with high quality peer review process for original research articles, review articles, short communi ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information

All correspondence should be addressed to:

Prof. Ibrahim Eldaghayes: Owner, Founder and Editor-in-Chief

Open Veterinary Journal


Faculty of Veterinary Medicine, University of Tripoli

P.O. Box 13662, Tripoli, Libya

and


Eldaghayes Publisher

www.eldagpublisher.com 

Email: ibrahim.eldaghayes@vetmed.edu.ly