E-ISSN 2218-6050 | ISSN 2226-4485
 

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Trypanosoma evansi: A clinical, parasitological and immunological evaluation of trypanosomosis using a chronic rabbit model

J.R. Ramírez-Iglesias, M.C. Eleizalde, E. Gómez-Piñeres and M. Mendoza*.


Abstract
We evaluated the clinical, parasitological and immunological effects of a Venezuelan strain of Trypanosoma evansi (T. evansi) throughout in experimentally inoculated rabbits over the course of infection and compared them with the same aspect in healthy animals. Body temperature was recorded in degrees Celsius, animal weight in kilograms, serum proteins in g/dl using a refractometer, haematocrit percentage by capillary centrifugation and the anti-T. evansi IgG titer by indirect ELISA immunoassay, from both infected animals and controls for 95 days. Infected animals showed a higher body temperature, total serum protein and anti- T. evansi antibody titer, and a lower haematocrit and weight gain than controls. These differences were related to the presence of the parasites in the blood as detected micro-haematocrit centrifugation technique (MHCT) and direct microscopic examination (DME). This study confirms the usefulness of rabbits as a model for the study of trypanosomosis; the clinical features of the disease can be observed and the three characteristic stages, prepatent period, acute and chronic phase clearly defined over the course of the infection

Key words: IgG, Temperature, Total serum protein, Trypanosomosis, Weight.


 
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How to Cite this Article
Pubmed Style

J.R. Ramírez-Iglesias, M.C. Eleizalde, E. Gómez-Piñeres and M. Mendoza. Trypanosoma evansi: A clinical, parasitological and immunological evaluation of trypanosomosis using a chronic rabbit model. Open Vet J. 2012; 2(0): 78-82. doi:10.5455/OVJ.2012.v2.i0.p78


Web Style

J.R. Ramírez-Iglesias, M.C. Eleizalde, E. Gómez-Piñeres and M. Mendoza. Trypanosoma evansi: A clinical, parasitological and immunological evaluation of trypanosomosis using a chronic rabbit model. https://www.openveterinaryjournal.com/?mno=302656792 [Access: July 13, 2024]. doi:10.5455/OVJ.2012.v2.i0.p78


AMA (American Medical Association) Style

J.R. Ramírez-Iglesias, M.C. Eleizalde, E. Gómez-Piñeres and M. Mendoza. Trypanosoma evansi: A clinical, parasitological and immunological evaluation of trypanosomosis using a chronic rabbit model. Open Vet J. 2012; 2(0): 78-82. doi:10.5455/OVJ.2012.v2.i0.p78



Vancouver/ICMJE Style

J.R. Ramírez-Iglesias, M.C. Eleizalde, E. Gómez-Piñeres and M. Mendoza. Trypanosoma evansi: A clinical, parasitological and immunological evaluation of trypanosomosis using a chronic rabbit model. Open Vet J. (2012), [cited July 13, 2024]; 2(0): 78-82. doi:10.5455/OVJ.2012.v2.i0.p78



Harvard Style

J.R. Ramírez-Iglesias, M.C. Eleizalde, E. Gómez-Piñeres and M. Mendoza (2012) Trypanosoma evansi: A clinical, parasitological and immunological evaluation of trypanosomosis using a chronic rabbit model. Open Vet J, 2 (0), 78-82. doi:10.5455/OVJ.2012.v2.i0.p78



Turabian Style

J.R. Ramírez-Iglesias, M.C. Eleizalde, E. Gómez-Piñeres and M. Mendoza. 2012. Trypanosoma evansi: A clinical, parasitological and immunological evaluation of trypanosomosis using a chronic rabbit model. Open Veterinary Journal, 2 (0), 78-82. doi:10.5455/OVJ.2012.v2.i0.p78



Chicago Style

J.R. Ramírez-Iglesias, M.C. Eleizalde, E. Gómez-Piñeres and M. Mendoza. "Trypanosoma evansi: A clinical, parasitological and immunological evaluation of trypanosomosis using a chronic rabbit model." Open Veterinary Journal 2 (2012), 78-82. doi:10.5455/OVJ.2012.v2.i0.p78



MLA (The Modern Language Association) Style

J.R. Ramírez-Iglesias, M.C. Eleizalde, E. Gómez-Piñeres and M. Mendoza. "Trypanosoma evansi: A clinical, parasitological and immunological evaluation of trypanosomosis using a chronic rabbit model." Open Veterinary Journal 2.0 (2012), 78-82. Print. doi:10.5455/OVJ.2012.v2.i0.p78



APA (American Psychological Association) Style

J.R. Ramírez-Iglesias, M.C. Eleizalde, E. Gómez-Piñeres and M. Mendoza (2012) Trypanosoma evansi: A clinical, parasitological and immunological evaluation of trypanosomosis using a chronic rabbit model. Open Veterinary Journal, 2 (0), 78-82. doi:10.5455/OVJ.2012.v2.i0.p78