E-ISSN 2218-6050 | ISSN 2226-4485
 

Short Communication


Possible Dysmetabolic Hyperferritinemia in Hyperinsulinemic Horses

Eleanor M Kellon, Kathleen M Gustafson.


Cited By:5

Abstract
Hyperinsulinemia associated with equine metabolic syndrome (EMS) and pituitary pars intermedia dysfunction (PPID) is a risk factor for laminitis. Research in other species has shown elevated body iron levels as both a predictor and consequence of insulin resistance. In humans this is known as dysmetabolic hyperferritinemia. We examined the relationship between insulin and the iron index most indicative of total body iron load [ferritin] in field cases of 33 horses with hyperinsulinemia. Serum ferritin exceeded published reference range for 100% of the horses. We also performed a secondary data analysis of published data and found significantly elevated ferritin (P = .05) in horses considered hyperinsulinemic by dynamic insulin testing compared to horses with a normal response. This preliminary retrospective data set should increase awareness of the potential for iron overload in hyperinsulinemic horses and stimulate further study into the relationship between insulin and iron dysregulation.

Key words: equine, ferritin, hyperinsulinemia,iron overload


 
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Pubmed Style

Kellon EM, Gustafson KM, . Possible Dysmetabolic Hyperferritinemia in Hyperinsulinemic Horses. Open Vet J. 2019; 9(4): 287-293. doi:10.4314/ovj.v9i4.2


Web Style

Kellon EM, Gustafson KM, . Possible Dysmetabolic Hyperferritinemia in Hyperinsulinemic Horses. https://www.openveterinaryjournal.com/?mno=36320 [Access: March 13, 2024]. doi:10.4314/ovj.v9i4.2


AMA (American Medical Association) Style

Kellon EM, Gustafson KM, . Possible Dysmetabolic Hyperferritinemia in Hyperinsulinemic Horses. Open Vet J. 2019; 9(4): 287-293. doi:10.4314/ovj.v9i4.2



Vancouver/ICMJE Style

Kellon EM, Gustafson KM, . Possible Dysmetabolic Hyperferritinemia in Hyperinsulinemic Horses. Open Vet J. (2019), [cited March 13, 2024]; 9(4): 287-293. doi:10.4314/ovj.v9i4.2



Harvard Style

Kellon, E. . M., Gustafson, K. M. & (2019) Possible Dysmetabolic Hyperferritinemia in Hyperinsulinemic Horses. Open Vet J, 9 (4), 287-293. doi:10.4314/ovj.v9i4.2



Turabian Style

Kellon, Eleanor M, Kathleen M Gustafson, and . 2019. Possible Dysmetabolic Hyperferritinemia in Hyperinsulinemic Horses. Open Veterinary Journal, 9 (4), 287-293. doi:10.4314/ovj.v9i4.2



Chicago Style

Kellon, Eleanor M, Kathleen M Gustafson, and . "Possible Dysmetabolic Hyperferritinemia in Hyperinsulinemic Horses." Open Veterinary Journal 9 (2019), 287-293. doi:10.4314/ovj.v9i4.2



MLA (The Modern Language Association) Style

Kellon, Eleanor M, Kathleen M Gustafson, and . "Possible Dysmetabolic Hyperferritinemia in Hyperinsulinemic Horses." Open Veterinary Journal 9.4 (2019), 287-293. Print. doi:10.4314/ovj.v9i4.2



APA (American Psychological Association) Style

Kellon, E. . M., Gustafson, K. M. & (2019) Possible Dysmetabolic Hyperferritinemia in Hyperinsulinemic Horses. Open Veterinary Journal, 9 (4), 287-293. doi:10.4314/ovj.v9i4.2