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2025, Vol: 15, Issue: 3
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Case Report


Long-term management of a cat with nasopharyngeal lymphoma by chlorambucil

Kaho Takahashi, Takashi Baba, Marin Hirokawa, Masaki Miyajima, Miori Kishimoto, Junpei Kimura, Hirotaka Kondo, Keitaro Ohmori.


Cited By:5

Abstract
Background: Lymphoma in the nasal cavity is the most common tumor of cats' upper respiratory tract. However, the effect of single-agent chlorambucil on nasal or nasopharyngeal lymphoma has not been evaluated in cats.
Case Description: An 8-year-old, castrated male Scottish Fold weighing 3.5 kg presented with an 8-month history of nasal discharge, sneezing, and mild epistaxis. CT and rhinoscopy revealed nasal discharge and slight swelling of the nasopharyngeal mucosa, but no masses and local invasions were detected. Histopathological and immunohistochemical analyses of the nasopharyngeal mucosa demonstrated B-cell lymphoma in the cat. The treatment with chlorambucil led to long-term management of the cat without any side effects. No recurrences of clinical signs have been observed for 754 days.
Conclusion: The present case report suggests that chlorambucil can be a therapeutic option for feline localized nasopharyngeal B-cell lymphoma without masses and local invasions.

Key words: cat, chlorambucil, lymphoma, nasal cavity, nasopharynx


 
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How to Cite this Article
Pubmed Style

Takahashi K, Baba T, Hirokawa M, Miyajima M, Kishimoto M, Kimura J, Kondo H, Ohmori K. Long-term management of a cat with nasopharyngeal lymphoma by chlorambucil. Open Vet J. 2021; 11(2): 217-221. doi:10.5455/OVJ.2021.v11.i2.5

Web Style

Takahashi K, Baba T, Hirokawa M, Miyajima M, Kishimoto M, Kimura J, Kondo H, Ohmori K. Long-term management of a cat with nasopharyngeal lymphoma by chlorambucil. https://www.openveterinaryjournal.com/?mno=50160 [Access: April 27, 2025]. doi:10.5455/OVJ.2021.v11.i2.5

AMA (American Medical Association) Style

Takahashi K, Baba T, Hirokawa M, Miyajima M, Kishimoto M, Kimura J, Kondo H, Ohmori K. Long-term management of a cat with nasopharyngeal lymphoma by chlorambucil. Open Vet J. 2021; 11(2): 217-221. doi:10.5455/OVJ.2021.v11.i2.5


Vancouver/ICMJE Style

Takahashi K, Baba T, Hirokawa M, Miyajima M, Kishimoto M, Kimura J, Kondo H, Ohmori K. Long-term management of a cat with nasopharyngeal lymphoma by chlorambucil. Open Vet J. (2021), [cited April 27, 2025]; 11(2): 217-221. doi:10.5455/OVJ.2021.v11.i2.5


Harvard Style

Takahashi, K., Baba, . T., Hirokawa, . M., Miyajima, . M., Kishimoto, . M., Kimura, . J., Kondo, . H. & Ohmori, . K. (2021) Long-term management of a cat with nasopharyngeal lymphoma by chlorambucil. Open Vet J, 11 (2), 217-221. doi:10.5455/OVJ.2021.v11.i2.5


Turabian Style

Takahashi, Kaho, Takashi Baba, Marin Hirokawa, Masaki Miyajima, Miori Kishimoto, Junpei Kimura, Hirotaka Kondo, and Keitaro Ohmori. 2021. Long-term management of a cat with nasopharyngeal lymphoma by chlorambucil. Open Veterinary Journal, 11 (2), 217-221. doi:10.5455/OVJ.2021.v11.i2.5


Chicago Style

Takahashi, Kaho, Takashi Baba, Marin Hirokawa, Masaki Miyajima, Miori Kishimoto, Junpei Kimura, Hirotaka Kondo, and Keitaro Ohmori. "Long-term management of a cat with nasopharyngeal lymphoma by chlorambucil." Open Veterinary Journal 11 (2021), 217-221. doi:10.5455/OVJ.2021.v11.i2.5


MLA (The Modern Language Association) Style

Takahashi, Kaho, Takashi Baba, Marin Hirokawa, Masaki Miyajima, Miori Kishimoto, Junpei Kimura, Hirotaka Kondo, and Keitaro Ohmori. "Long-term management of a cat with nasopharyngeal lymphoma by chlorambucil." Open Veterinary Journal 11.2 (2021), 217-221. Print. doi:10.5455/OVJ.2021.v11.i2.5


APA (American Psychological Association) Style

Takahashi, K., Baba, . T., Hirokawa, . M., Miyajima, . M., Kishimoto, . M., Kimura, . J., Kondo, . H. & Ohmori, . K. (2021) Long-term management of a cat with nasopharyngeal lymphoma by chlorambucil. Open Veterinary Journal, 11 (2), 217-221. doi:10.5455/OVJ.2021.v11.i2.5


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