E-ISSN 2218-6050 | ISSN 2226-4485
 
2025, Vol: 15, Issue: 2
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Original Article


Treatment of canine osteoarthritis with allogenic platelet rich plasma: review of five cases

Jose Catarino, Pedro Pires Carvalho, Sara Santos, Angela Martins, Joao Filipe Requicha.


Cited By:32

Abstract
Background: Osteoarthritis (OA) is the major cause of chronic pain in dogs. Platelet-rich plasma (PRP) is a concentrate of growth and differentiation factors from the blood, which can be used in Regenerative Medicine strategies.
Aim: The main aim of this study was to evaluate the effect of allogenic PRP on the treatment of canine osteoarthritis.
Methods: Five dogs from several breeds, between 6 and 12 years old and from both genders were studied. Clinical and imagiological exams diagnosed OA in the knee, tibiotarsi, elbow and intercarpal joints. These dogs were refractory to medical therapy and to physical rehabilitation protocols that included shockwave therapy, LASER therapy, electrostimulation and hydrotherapy and diathermy.
Animals were treated with allogenic PRP obtained from the blood of the five dogs which was processed in a pool. Ecoguided intraarticular PRP injection was performed under sedation and after aseptic field preparation. Lameness at walk and trot (5 levels) and pain (5 levels) were evaluated before treatment and 30, 60 and 90 days post-treatment.
Results: All animals presented improvements at 30 and 60 days in both parameters. Four dogs showed decrease of three levels of lameness after 90 days and complete absence was shown in two. Pain was reduced from severe and moderate to mild in all dogs after 30 days and, among them, three revealed no pain after 90 days.
Conclusion: This study sheds light on the applicability and safety of single administration of allogenic PRP in osteoarthritic dogs.

Key words: Dog, Osteoarthritis, Lameness, Pain, Platelet-rich plasma.


 
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How to Cite this Article
Pubmed Style

Catarino J, Carvalho PP, Santos S, Martins A, Requicha JF. Treatment of canine osteoarthritis with allogenic platelet rich plasma: review of five cases. Open Vet J. 2020; 10(2): 226-231. doi:10.4314/ovj.v10i2.12

Web Style

Catarino J, Carvalho PP, Santos S, Martins A, Requicha JF. Treatment of canine osteoarthritis with allogenic platelet rich plasma: review of five cases. https://www.openveterinaryjournal.com/?mno=85058 [Access: March 18, 2025]. doi:10.4314/ovj.v10i2.12

AMA (American Medical Association) Style

Catarino J, Carvalho PP, Santos S, Martins A, Requicha JF. Treatment of canine osteoarthritis with allogenic platelet rich plasma: review of five cases. Open Vet J. 2020; 10(2): 226-231. doi:10.4314/ovj.v10i2.12


Vancouver/ICMJE Style

Catarino J, Carvalho PP, Santos S, Martins A, Requicha JF. Treatment of canine osteoarthritis with allogenic platelet rich plasma: review of five cases. Open Vet J. (2020), [cited March 18, 2025]; 10(2): 226-231. doi:10.4314/ovj.v10i2.12


Harvard Style

Catarino, J., Carvalho, . P. P., Santos, . S., Martins, . A. & Requicha, . J. F. (2020) Treatment of canine osteoarthritis with allogenic platelet rich plasma: review of five cases. Open Vet J, 10 (2), 226-231. doi:10.4314/ovj.v10i2.12


Turabian Style

Catarino, Jose, Pedro Pires Carvalho, Sara Santos, Angela Martins, and Joao Filipe Requicha. 2020. Treatment of canine osteoarthritis with allogenic platelet rich plasma: review of five cases. Open Veterinary Journal, 10 (2), 226-231. doi:10.4314/ovj.v10i2.12


Chicago Style

Catarino, Jose, Pedro Pires Carvalho, Sara Santos, Angela Martins, and Joao Filipe Requicha. "Treatment of canine osteoarthritis with allogenic platelet rich plasma: review of five cases." Open Veterinary Journal 10 (2020), 226-231. doi:10.4314/ovj.v10i2.12


MLA (The Modern Language Association) Style

Catarino, Jose, Pedro Pires Carvalho, Sara Santos, Angela Martins, and Joao Filipe Requicha. "Treatment of canine osteoarthritis with allogenic platelet rich plasma: review of five cases." Open Veterinary Journal 10.2 (2020), 226-231. Print. doi:10.4314/ovj.v10i2.12


APA (American Psychological Association) Style

Catarino, J., Carvalho, . P. P., Santos, . S., Martins, . A. & Requicha, . J. F. (2020) Treatment of canine osteoarthritis with allogenic platelet rich plasma: review of five cases. Open Veterinary Journal, 10 (2), 226-231. doi:10.4314/ovj.v10i2.12


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