E-ISSN 2218-6050 | ISSN 2226-4485
 
2024, Vol: 14, Issue: 11
14 / 11Current Issue ArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles
Required files to be uploaded

OVJ Manuscript Submission Form

Research Article


The immunostimulatory effects of fucoidan on the cellular and humoral immune response in Wistar rats

Rochmah Kurnijasanti, Giftania Wardani, Muhammad Rais Mustafa, Sri Agus Sudjarwo.


Abstract
Background:
Natural product active ingredients are currently being studied rigorously worldwide and offer a viable substitute for traditional immunotherapy for various medical disorders.
Aim:
The objective of the study was to investigate the immunostimulatory properties of fucoidan in albino Wistar rats.
Methods:
For the current study, forty rats were divided into five groups of rats that were used in good condition. In-vivo experiments of fucoidan were carried out in Wistar albino rats, such as the cyclophosphamide-caused myelosuppression, the delayed-type hypersensitivity (DTH) response, the phagocytic activity, the haemagglutinating antibody (HA) titer, and the neutrophil adhesion test.
Results:
The phagocytic index increased significantly in response to Fucoidan in a dose-dependent manner, as well as enhanced DTH reaction, and HA titer caused by sheep red blood cells sheep red blood cells. Additionally, fucoidan decreased myelosuppression in rats after cyclophosphamide treatment and enhanced neutrophil adhesion with nylon f iber.
Conclusion:
These findings imply that fucoidan has immunostimulant properties and could potentially utilised to treat immune-depression diseases.

Key words: Fucoidan, Immunostimulant, Humoral immune response, Cellular immune response


 
ARTICLE TOOLS
Abstract
PDF Fulltext
HTML Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Rochmah Kurnijasanti
Articles by Giftania Wardani
Articles by Muhammad Rais Mustafa
Articles by Sri Agus Sudjarwo
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Kurnijasanti R, Wardani G, Mustafa MR, Sudjarwo SA. The immunostimulatory effects of fucoidan on the cellular and humoral immune response in Wistar rats. Open Vet J. 2024; 14(8): 1794-1800. doi:10.5455/OVJ.2024.v14.i8.7

Web Style

Kurnijasanti R, Wardani G, Mustafa MR, Sudjarwo SA. The immunostimulatory effects of fucoidan on the cellular and humoral immune response in Wistar rats. https://www.openveterinaryjournal.com/?mno=194485 [Access: December 03, 2024]. doi:10.5455/OVJ.2024.v14.i8.7

AMA (American Medical Association) Style

Kurnijasanti R, Wardani G, Mustafa MR, Sudjarwo SA. The immunostimulatory effects of fucoidan on the cellular and humoral immune response in Wistar rats. Open Vet J. 2024; 14(8): 1794-1800. doi:10.5455/OVJ.2024.v14.i8.7


Vancouver/ICMJE Style

Kurnijasanti R, Wardani G, Mustafa MR, Sudjarwo SA. The immunostimulatory effects of fucoidan on the cellular and humoral immune response in Wistar rats. Open Vet J. (2024), [cited December 03, 2024]; 14(8): 1794-1800. doi:10.5455/OVJ.2024.v14.i8.7


Harvard Style

Kurnijasanti, R., Wardani, . G., Mustafa, . M. R. & Sudjarwo, . S. A. (2024) The immunostimulatory effects of fucoidan on the cellular and humoral immune response in Wistar rats. Open Vet J, 14 (8), 1794-1800. doi:10.5455/OVJ.2024.v14.i8.7


Turabian Style

Kurnijasanti, Rochmah, Giftania Wardani, Muhammad Rais Mustafa, and Sri Agus Sudjarwo. 2024. The immunostimulatory effects of fucoidan on the cellular and humoral immune response in Wistar rats. Open Veterinary Journal, 14 (8), 1794-1800. doi:10.5455/OVJ.2024.v14.i8.7


Chicago Style

Kurnijasanti, Rochmah, Giftania Wardani, Muhammad Rais Mustafa, and Sri Agus Sudjarwo. "The immunostimulatory effects of fucoidan on the cellular and humoral immune response in Wistar rats." Open Veterinary Journal 14 (2024), 1794-1800. doi:10.5455/OVJ.2024.v14.i8.7


MLA (The Modern Language Association) Style

Kurnijasanti, Rochmah, Giftania Wardani, Muhammad Rais Mustafa, and Sri Agus Sudjarwo. "The immunostimulatory effects of fucoidan on the cellular and humoral immune response in Wistar rats." Open Veterinary Journal 14.8 (2024), 1794-1800. Print. doi:10.5455/OVJ.2024.v14.i8.7


APA (American Psychological Association) Style

Kurnijasanti, R., Wardani, . G., Mustafa, . M. R. & Sudjarwo, . S. A. (2024) The immunostimulatory effects of fucoidan on the cellular and humoral immune response in Wistar rats. Open Veterinary Journal, 14 (8), 1794-1800. doi:10.5455/OVJ.2024.v14.i8.7


Author LoginReviewer LoginAbout PublisherPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyTerms of UseLicense Information

About Open Veterinary Journal

Open Veterinary Journal provides a fast track coupled with high quality peer review process for original research articles, review articles, short communi ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information

All correspondence should be addressed to:

Prof. Ibrahim Eldaghayes: Owner, Founder and Editor-in-Chief

Open Veterinary Journal


Faculty of Veterinary Medicine, University of Tripoli

P.O. Box 13662, Tripoli, Libya

and


Eldaghayes Publisher

www.eldagpublisher.com 

Email: ibrahim.eldaghayes@vetmed.edu.ly