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Research Article


The potential of Myrmecodia pendans in preventing complications of diabetes mellitus as an antidiabetic and antihyperlipidemic agent

Milahayati Daulay, Muhammad Syahputra, Mutiara Indah Sari, Tri Widyawati, Dwi Rita Anggraini.


Abstract
Background:
Hyperglycemia in diabetes mellitus (DM) can lead to dyslipidemia, which is a risk factor for macrovascular complications such as heart disease and stroke. Aside from administering antidiabetic medications, DM treatment can also be achieved through the use of natural components, such as Myrmecodia pendans, commonly known as the ant nest plant.
Aim:
This study aimed to investigate the impact of administering the ant nest plant on the lipid profile of Wistar rats.
Methods:
A group of 20 rats was divided into two categories: 6 rats served as healthy controls (H), while the remaining 14 rats were subjected to a high-lipid diet and streptozotocin to generate a model of type 2 diabetes mellitus (T2DM). The diabetic rats were divided into two groups: the DM group consisted of rats that did not receive any treatment, while the ant nest plant (ANP) group was administered the herb orally.
Results:
The results revealed significant variations in triglyceride, high-density lipoprotein (HDL), and low-density lipoprotein (LDL) levels among the three groups (p<0.05). The post hoc test revealed disparities in triglyceride and LDL between those with DM group and ANP group (p<0.05).
Conclusion:
Myrmecodia pendans demonstrated the ability to decrease triglyceride and LDL, while increasing HDL levels in rats with T2DM.

Key words: Myrmecodia pendans, Ant nest plant, Diabetes mellitus, Cholesterol


 
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How to Cite this Article
Pubmed Style

Daulay M, Syahputra M, Sari MI, Widyawati T, Anggraini DR. The potential of Myrmecodia pendans in preventing complications of diabetes mellitus as an antidiabetic and antihyperlipidemic agent. Open Vet J. 2024; 14(7): 1607-1613. doi:10.5455/OVJ.2024.v14.i7.10

Web Style

Daulay M, Syahputra M, Sari MI, Widyawati T, Anggraini DR. The potential of Myrmecodia pendans in preventing complications of diabetes mellitus as an antidiabetic and antihyperlipidemic agent. https://www.openveterinaryjournal.com/?mno=197971 [Access: December 07, 2024]. doi:10.5455/OVJ.2024.v14.i7.10

AMA (American Medical Association) Style

Daulay M, Syahputra M, Sari MI, Widyawati T, Anggraini DR. The potential of Myrmecodia pendans in preventing complications of diabetes mellitus as an antidiabetic and antihyperlipidemic agent. Open Vet J. 2024; 14(7): 1607-1613. doi:10.5455/OVJ.2024.v14.i7.10


Vancouver/ICMJE Style

Daulay M, Syahputra M, Sari MI, Widyawati T, Anggraini DR. The potential of Myrmecodia pendans in preventing complications of diabetes mellitus as an antidiabetic and antihyperlipidemic agent. Open Vet J. (2024), [cited December 07, 2024]; 14(7): 1607-1613. doi:10.5455/OVJ.2024.v14.i7.10


Harvard Style

Daulay, M., Syahputra, . M., Sari, . M. I., Widyawati, . T. & Anggraini, . D. R. (2024) The potential of Myrmecodia pendans in preventing complications of diabetes mellitus as an antidiabetic and antihyperlipidemic agent. Open Vet J, 14 (7), 1607-1613. doi:10.5455/OVJ.2024.v14.i7.10


Turabian Style

Daulay, Milahayati, Muhammad Syahputra, Mutiara Indah Sari, Tri Widyawati, and Dwi Rita Anggraini. 2024. The potential of Myrmecodia pendans in preventing complications of diabetes mellitus as an antidiabetic and antihyperlipidemic agent. Open Veterinary Journal, 14 (7), 1607-1613. doi:10.5455/OVJ.2024.v14.i7.10


Chicago Style

Daulay, Milahayati, Muhammad Syahputra, Mutiara Indah Sari, Tri Widyawati, and Dwi Rita Anggraini. "The potential of Myrmecodia pendans in preventing complications of diabetes mellitus as an antidiabetic and antihyperlipidemic agent." Open Veterinary Journal 14 (2024), 1607-1613. doi:10.5455/OVJ.2024.v14.i7.10


MLA (The Modern Language Association) Style

Daulay, Milahayati, Muhammad Syahputra, Mutiara Indah Sari, Tri Widyawati, and Dwi Rita Anggraini. "The potential of Myrmecodia pendans in preventing complications of diabetes mellitus as an antidiabetic and antihyperlipidemic agent." Open Veterinary Journal 14.7 (2024), 1607-1613. Print. doi:10.5455/OVJ.2024.v14.i7.10


APA (American Psychological Association) Style

Daulay, M., Syahputra, . M., Sari, . M. I., Widyawati, . T. & Anggraini, . D. R. (2024) The potential of Myrmecodia pendans in preventing complications of diabetes mellitus as an antidiabetic and antihyperlipidemic agent. Open Veterinary Journal, 14 (7), 1607-1613. doi:10.5455/OVJ.2024.v14.i7.10


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