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2024, Vol: 14, Issue: 12
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A review of myostatin gene mutations: Enhancing meat production and potential in livestock genetic selection

Siti Rani Ayuti, Mirni Lamid, Sunaryo Hadi Warsito, Mohammad Anam Al-arif, Widya Paramita Lokapirnasari, Zulfi Nur Amrina Rosyada, Sugito Sugito, Muslim Akmal, Rimayanti Rimayanti, Rakhi Gangil, Aswin Rafif Khairullah, Mutasem Abuzahra, Ikechukwu Benjamin Moses, Lili Anggraini.


Abstract
Myostatin (MSTN) is an essential gene that regulates muscle growth and development in livestock animals, influencing meat production and carcass quality. This review looks at myostatin genetic diversity in a variety of animals, including cattle, sheep, goats, and poultry, focusing on correlations between particular mutations and phenotypic parameters like muscle mass and growth rate. Mutations in the MSTN gene have been linked to desirable features such as greater body weight and higher meat quality, making it an ideal candidate for genetic selection in breeding programs. Animals carrying this mutation frequently transform feed into muscle more efficiently, resulting in faster growth with less feed input. This is advantageous for growers seeking to cut feed costs while raising yields. MSTN-mutated animals convert feed into muscle more efficiently, lowering production costs over time and making them more appealing for commercial breeding operations. Advances in molecular genetics, especially CRISPR-Cas9 technology, have made it possible to precisely manipulate the myostatin gene, allowing for the development of calves with enhanced muscle mass. This article also examines the effects of myostatin variation on meat production efficiency, as well as current issues in animal genetics. This research synthesis emphasizes the significance of myostatin in cattle breeding, specifically its potential as a genetic marker to improve production and meat quality in commercial farming.

Key words: Growth, Poultry, Productivity, Muscle, Myostatin


 
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How to Cite this Article
Pubmed Style

Ayuti SR, Lamid M, Warsito SH, Al-arif MA, Lokapirnasari WP, Rosyada ZNA, Sugito S, Akmal M, Rimayanti R, Gangil R, Khairullah AR, Abuzahra M, Moses IB, Anggraini L. A review of myostatin gene mutations: Enhancing meat production and potential in livestock genetic selection. Open Vet J. 2024; 14(12): 3189-3202. doi:10.5455/OVJ.2024.v14.i12.4

Web Style

Ayuti SR, Lamid M, Warsito SH, Al-arif MA, Lokapirnasari WP, Rosyada ZNA, Sugito S, Akmal M, Rimayanti R, Gangil R, Khairullah AR, Abuzahra M, Moses IB, Anggraini L. A review of myostatin gene mutations: Enhancing meat production and potential in livestock genetic selection. https://www.openveterinaryjournal.com/?mno=226905 [Access: January 22, 2025]. doi:10.5455/OVJ.2024.v14.i12.4

AMA (American Medical Association) Style

Ayuti SR, Lamid M, Warsito SH, Al-arif MA, Lokapirnasari WP, Rosyada ZNA, Sugito S, Akmal M, Rimayanti R, Gangil R, Khairullah AR, Abuzahra M, Moses IB, Anggraini L. A review of myostatin gene mutations: Enhancing meat production and potential in livestock genetic selection. Open Vet J. 2024; 14(12): 3189-3202. doi:10.5455/OVJ.2024.v14.i12.4


Vancouver/ICMJE Style

Ayuti SR, Lamid M, Warsito SH, Al-arif MA, Lokapirnasari WP, Rosyada ZNA, Sugito S, Akmal M, Rimayanti R, Gangil R, Khairullah AR, Abuzahra M, Moses IB, Anggraini L. A review of myostatin gene mutations: Enhancing meat production and potential in livestock genetic selection. Open Vet J. (2024), [cited January 22, 2025]; 14(12): 3189-3202. doi:10.5455/OVJ.2024.v14.i12.4


Harvard Style

Ayuti, S. R., Lamid, . M., Warsito, . S. H., Al-arif, . M. A., Lokapirnasari, . W. P., Rosyada, . Z. N. A., Sugito, . S., Akmal, . M., Rimayanti, . R., Gangil, . R., Khairullah, . A. R., Abuzahra, . M., Moses, . I. B. & Anggraini, . L. (2024) A review of myostatin gene mutations: Enhancing meat production and potential in livestock genetic selection. Open Vet J, 14 (12), 3189-3202. doi:10.5455/OVJ.2024.v14.i12.4


Turabian Style

Ayuti, Siti Rani, Mirni Lamid, Sunaryo Hadi Warsito, Mohammad Anam Al-arif, Widya Paramita Lokapirnasari, Zulfi Nur Amrina Rosyada, Sugito Sugito, Muslim Akmal, Rimayanti Rimayanti, Rakhi Gangil, Aswin Rafif Khairullah, Mutasem Abuzahra, Ikechukwu Benjamin Moses, and Lili Anggraini. 2024. A review of myostatin gene mutations: Enhancing meat production and potential in livestock genetic selection. Open Veterinary Journal, 14 (12), 3189-3202. doi:10.5455/OVJ.2024.v14.i12.4


Chicago Style

Ayuti, Siti Rani, Mirni Lamid, Sunaryo Hadi Warsito, Mohammad Anam Al-arif, Widya Paramita Lokapirnasari, Zulfi Nur Amrina Rosyada, Sugito Sugito, Muslim Akmal, Rimayanti Rimayanti, Rakhi Gangil, Aswin Rafif Khairullah, Mutasem Abuzahra, Ikechukwu Benjamin Moses, and Lili Anggraini. "A review of myostatin gene mutations: Enhancing meat production and potential in livestock genetic selection." Open Veterinary Journal 14 (2024), 3189-3202. doi:10.5455/OVJ.2024.v14.i12.4


MLA (The Modern Language Association) Style

Ayuti, Siti Rani, Mirni Lamid, Sunaryo Hadi Warsito, Mohammad Anam Al-arif, Widya Paramita Lokapirnasari, Zulfi Nur Amrina Rosyada, Sugito Sugito, Muslim Akmal, Rimayanti Rimayanti, Rakhi Gangil, Aswin Rafif Khairullah, Mutasem Abuzahra, Ikechukwu Benjamin Moses, and Lili Anggraini. "A review of myostatin gene mutations: Enhancing meat production and potential in livestock genetic selection." Open Veterinary Journal 14.12 (2024), 3189-3202. Print. doi:10.5455/OVJ.2024.v14.i12.4


APA (American Psychological Association) Style

Ayuti, S. R., Lamid, . M., Warsito, . S. H., Al-arif, . M. A., Lokapirnasari, . W. P., Rosyada, . Z. N. A., Sugito, . S., Akmal, . M., Rimayanti, . R., Gangil, . R., Khairullah, . A. R., Abuzahra, . M., Moses, . I. B. & Anggraini, . L. (2024) A review of myostatin gene mutations: Enhancing meat production and potential in livestock genetic selection. Open Veterinary Journal, 14 (12), 3189-3202. doi:10.5455/OVJ.2024.v14.i12.4


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