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2025, Vol: 15, Issue: 12
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Case Report


Improvement in coat condition observed in dogs with suspected alopecia X through combined supplementation with nutrients for the coat and skin: A case report

Atsuhiro Murayama, Kentarou Tahara, Eiichi Hirano.


Abstract
Background:
Alopecia X is characterized by non-inflammatory hair loss and is commonly observed in dog breeds with double coats and dense undercoats. The exact cause of alopecia X remains unknown, and its complex etiology and diverse responses to treatment make it a challenging condition for veterinarians to manage.

Case Description:
An 8-year-old Chihuahua (male, unneutered, weight 4.1 kg) with significant hair loss was brought to our clinic. The owner declined to provide a definitive diagnosis; consequently, a diagnosis of suspected alopecia was made based on a physical examination and a series of questions. Horse placenta extract, taurine, and vitamin B complex (B1, B2, B5, and B6) were administered as non-pharmacological therapies. Following a 66-day supplementation regimen, a marked improvement in hair coat coverage was observed, with the back, sides, and abdomen exhibiting near-full-coat coverage. No adverse events were observed during the supplementation period. Following an enhancement in coat condition, supplementation was terminated, and no hair loss was observed during a 76-week follow-up period.

Conclusion:
The combination of supplements from different categories may be a novel treatment option for owners who wish to pursue non-invasive treatment for alopecia for their dogs.

Key words: Alopecia X; Dog; Combination therapy; Nutrient supplementation.


 
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How to Cite this Article
Pubmed Style

Murayama A, Tahara K, Hirano E. Improvement in coat condition observed in dogs with suspected alopecia X through combined supplementation with nutrients for the coat and skin: A case report. Open Vet. J.. 2025; 15(12): 6809-6813. doi:10.5455/OVJ.2025.v15.i12.60

Web Style

Murayama A, Tahara K, Hirano E. Improvement in coat condition observed in dogs with suspected alopecia X through combined supplementation with nutrients for the coat and skin: A case report. https://www.openveterinaryjournal.com/?mno=284389 [Access: December 31, 2025]. doi:10.5455/OVJ.2025.v15.i12.60

AMA (American Medical Association) Style

Murayama A, Tahara K, Hirano E. Improvement in coat condition observed in dogs with suspected alopecia X through combined supplementation with nutrients for the coat and skin: A case report. Open Vet. J.. 2025; 15(12): 6809-6813. doi:10.5455/OVJ.2025.v15.i12.60


Vancouver/ICMJE Style

Murayama A, Tahara K, Hirano E. Improvement in coat condition observed in dogs with suspected alopecia X through combined supplementation with nutrients for the coat and skin: A case report. Open Vet. J.. (2025), [cited December 31, 2025]; 15(12): 6809-6813. doi:10.5455/OVJ.2025.v15.i12.60


Harvard Style

Murayama, A., Tahara, . K. & Hirano, . E. (2025) Improvement in coat condition observed in dogs with suspected alopecia X through combined supplementation with nutrients for the coat and skin: A case report. Open Vet. J., 15 (12), 6809-6813. doi:10.5455/OVJ.2025.v15.i12.60


Turabian Style

Murayama, Atsuhiro, Kentarou Tahara, and Eiichi Hirano. 2025. Improvement in coat condition observed in dogs with suspected alopecia X through combined supplementation with nutrients for the coat and skin: A case report. Open Veterinary Journal, 15 (12), 6809-6813. doi:10.5455/OVJ.2025.v15.i12.60


Chicago Style

Murayama, Atsuhiro, Kentarou Tahara, and Eiichi Hirano. "Improvement in coat condition observed in dogs with suspected alopecia X through combined supplementation with nutrients for the coat and skin: A case report." Open Veterinary Journal 15 (2025), 6809-6813. doi:10.5455/OVJ.2025.v15.i12.60


MLA (The Modern Language Association) Style

Murayama, Atsuhiro, Kentarou Tahara, and Eiichi Hirano. "Improvement in coat condition observed in dogs with suspected alopecia X through combined supplementation with nutrients for the coat and skin: A case report." Open Veterinary Journal 15.12 (2025), 6809-6813. Print. doi:10.5455/OVJ.2025.v15.i12.60


APA (American Psychological Association) Style

Murayama, A., Tahara, . K. & Hirano, . E. (2025) Improvement in coat condition observed in dogs with suspected alopecia X through combined supplementation with nutrients for the coat and skin: A case report. Open Veterinary Journal, 15 (12), 6809-6813. doi:10.5455/OVJ.2025.v15.i12.60


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