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Case Report


Localized fungal osteomyelitis caused by Aspergillus sp. in the ilium and acetabulum of a dog with disseminated aspergillosis: A case report

João Domingos Rocha Júnior, Letícia Fornel Mangolin, Igor Bruno Oliveira Da Silva, Lara Cristina De Melo Lopes, João Pedro Garcia Luvisoto, Thaylla Maria Ferreira, Isadora Pezati Sabino, Alef Winter Oliveira Alvarenga, Jessé Ribeiro Rocha, Fernanda Gosuen Gonçalves Dias.


Abstract
Background:
Osteomyelitis caused by Aspergillus sp. is uncommon in dogs and cats and may occur in cases of disseminated aspergillosis, a rare and poorly described condition in veterinary medicine.

Case Description:
Due to the scarcity of reports documenting this disease, particularly with localized involvement of the pelvic bones, the present case report aimed to describe the condition in an eight-year-old mixed-breed dog presenting with severe pain and lameness of the right pelvic limb. Radiographic examination revealed marked periosteal bone proliferation and areas of osteolysis extending from the right wing of the ilium to the acetabulum. Incisional biopsy demonstrated a dense inflammatory infiltrate consistent with chronic osteitis and myositis. Samples were submitted for bacterial and fungal cultures, with growth observed only in the fungal culture, identifying Aspergillus species. Treatment with itraconazole at 10 mg/kg every 24 hours was initiated, and therapeutic response was monitored through periodic radiographs, which showed gradual regression of the initial lesions.

Conclusion:
At the time of this report, 16 months after treatment initiation, the patient exhibited continuous clinical improvement without systemic signs of disease, indicating therapeutic success and a longer survival expectancy.

Key words: Aspergillosis; Itraconazole; Osteomyelitis; Systemic mycosis; Veterinary mycology.


 
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How to Cite this Article
Pubmed Style

Júnior JDR, Mangolin LF, Silva IBOD, Lopes LCDM, Luvisoto JPG, Ferreira TM, Sabino IP, Alvarenga AWO, Rocha JR, Dias FGG. Localized fungal osteomyelitis caused by Aspergillus sp. in the ilium and acetabulum of a dog with disseminated aspergillosis: A case report. Open Vet. J.. 2026; 16(2): 1369-1379. doi:10.5455/OVJ.2026.v16.i2.53

Web Style

Júnior JDR, Mangolin LF, Silva IBOD, Lopes LCDM, Luvisoto JPG, Ferreira TM, Sabino IP, Alvarenga AWO, Rocha JR, Dias FGG. Localized fungal osteomyelitis caused by Aspergillus sp. in the ilium and acetabulum of a dog with disseminated aspergillosis: A case report. https://www.openveterinaryjournal.com/?mno=289713 [Access: February 27, 2026]. doi:10.5455/OVJ.2026.v16.i2.53

AMA (American Medical Association) Style

Júnior JDR, Mangolin LF, Silva IBOD, Lopes LCDM, Luvisoto JPG, Ferreira TM, Sabino IP, Alvarenga AWO, Rocha JR, Dias FGG. Localized fungal osteomyelitis caused by Aspergillus sp. in the ilium and acetabulum of a dog with disseminated aspergillosis: A case report. Open Vet. J.. 2026; 16(2): 1369-1379. doi:10.5455/OVJ.2026.v16.i2.53


Vancouver/ICMJE Style

Júnior JDR, Mangolin LF, Silva IBOD, Lopes LCDM, Luvisoto JPG, Ferreira TM, Sabino IP, Alvarenga AWO, Rocha JR, Dias FGG. Localized fungal osteomyelitis caused by Aspergillus sp. in the ilium and acetabulum of a dog with disseminated aspergillosis: A case report. Open Vet. J.. (2026), [cited February 27, 2026]; 16(2): 1369-1379. doi:10.5455/OVJ.2026.v16.i2.53


Harvard Style

Júnior, J. D. R., Mangolin, . L. F., Silva, . I. B. O. D., Lopes, . L. C. D. M., Luvisoto, . J. P. G., Ferreira, . T. M., Sabino, . I. P., Alvarenga, . A. W. O., Rocha, . J. R. & Dias, . F. G. G. (2026) Localized fungal osteomyelitis caused by Aspergillus sp. in the ilium and acetabulum of a dog with disseminated aspergillosis: A case report. Open Vet. J., 16 (2), 1369-1379. doi:10.5455/OVJ.2026.v16.i2.53


Turabian Style

Júnior, João Domingos Rocha, Letícia Fornel Mangolin, Igor Bruno Oliveira Da Silva, Lara Cristina De Melo Lopes, João Pedro Garcia Luvisoto, Thaylla Maria Ferreira, Isadora Pezati Sabino, Alef Winter Oliveira Alvarenga, Jessé Ribeiro Rocha, and Fernanda Gosuen Goncalves Dias. 2026. Localized fungal osteomyelitis caused by Aspergillus sp. in the ilium and acetabulum of a dog with disseminated aspergillosis: A case report. Open Veterinary Journal, 16 (2), 1369-1379. doi:10.5455/OVJ.2026.v16.i2.53


Chicago Style

Júnior, João Domingos Rocha, Letícia Fornel Mangolin, Igor Bruno Oliveira Da Silva, Lara Cristina De Melo Lopes, João Pedro Garcia Luvisoto, Thaylla Maria Ferreira, Isadora Pezati Sabino, Alef Winter Oliveira Alvarenga, Jessé Ribeiro Rocha, and Fernanda Gosuen Goncalves Dias. "Localized fungal osteomyelitis caused by Aspergillus sp. in the ilium and acetabulum of a dog with disseminated aspergillosis: A case report." Open Veterinary Journal 16 (2026), 1369-1379. doi:10.5455/OVJ.2026.v16.i2.53


MLA (The Modern Language Association) Style

Júnior, João Domingos Rocha, Letícia Fornel Mangolin, Igor Bruno Oliveira Da Silva, Lara Cristina De Melo Lopes, João Pedro Garcia Luvisoto, Thaylla Maria Ferreira, Isadora Pezati Sabino, Alef Winter Oliveira Alvarenga, Jessé Ribeiro Rocha, and Fernanda Gosuen Goncalves Dias. "Localized fungal osteomyelitis caused by Aspergillus sp. in the ilium and acetabulum of a dog with disseminated aspergillosis: A case report." Open Veterinary Journal 16.2 (2026), 1369-1379. Print. doi:10.5455/OVJ.2026.v16.i2.53


APA (American Psychological Association) Style

Júnior, J. D. R., Mangolin, . L. F., Silva, . I. B. O. D., Lopes, . L. C. D. M., Luvisoto, . J. P. G., Ferreira, . T. M., Sabino, . I. P., Alvarenga, . A. W. O., Rocha, . J. R. & Dias, . F. G. G. (2026) Localized fungal osteomyelitis caused by Aspergillus sp. in the ilium and acetabulum of a dog with disseminated aspergillosis: A case report. Open Veterinary Journal, 16 (2), 1369-1379. doi:10.5455/OVJ.2026.v16.i2.53


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