E-ISSN 2218-6050 | ISSN 2226-4485
 
2024, Vol: 14, Issue: 11
14 / 11Current Issue ArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles
Required files to be uploaded

OVJ Manuscript Submission Form

Original Article


A survey of contagious ecthyma and molecular characterization of Orf virus in sheep and goats in Nigeria (2014-2016)

Adeyinka Jeremy Adedeji, Jolly Amoche Adole, Olayinka Oluwafemi Asala, Ahmed Abdulkadir Abdulkadir Gamawa , Nanven Abraham Maurice, Anvou Jambol, Mohammed Bashir Bolajoko, Nneka Chineze Chima, Victoria Isioma Ifende, Yiltawe Simwal Wungak, Timothy Yusufu Woma , Pam Dachung Luka.


Cited By:3

Abstract
Background: Outbreaks of contagious ecthyma (CE) are frequently reported in sheep and goats flocks in Nigeria with severe clinical outcomes. CE is a debilitating and economically important disease primarily affecting sheep and goats caused by the Orf virus (ORFV). Despite field reports of CE in the country, there is no concise country-wide epidemiological data on the disease and limited genetic data of circulating Nigerian ORFV are available in the public domain.
Aim: An epidemiological survey of CE and molecular characterization of ORFV circulating in Nigeria from 2014-2016
Method: Data were collected using questionnaires designed and administered to veterinarians and farmers in selected States of Nigeria. Samples collected during passive surveillance for CE from 2014 to 2016 were analyzed by polymerase chain reaction (PCR). The A32L and B2L genes of circulating ORFV were characterized.
Results: Analysis of the questionnaire showed that 69.54% (n=82/118) of the farmers claimed to have experienced CE in their flocks with average morbidity and mortality rates of 25% and 15%, respectively. A total of 113 veterinarians participated in the study, with 69.9% (n=79) familiar with CE and claimed CE causes morbidity rates of 25%-37% and mortality rates of 10%-15% in sheep and goats. Laboratory results revealed that ORFV was detected in 72% (18/25) of outbreak samples analyzed by Real-time PCR. Phylogenetic analysis of A32L and B2L genes revealed that Nigerian ORFV sequences belong to cluster I and II and are similar to viruses from India, Ethiopia and China.
Conclusions: This study is the first nationwide epidemiological data on the status of CE in sheep and goats in Nigeria. It is also the first report of molecular characterization of two genes of ORFV circulating and causing outbreaks in small ruminants in the country. This study showed that CE is under-reported, widespread and of economic importance to sheep and goat farmers in Nigeria.

Key words: A32L gene, B2L gene, Contagious ecthyma, Orf virus, small ruminants, Nigeria.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
HTML Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Adeyinka Jeremy Adedeji
Articles by Jolly Amoche Adole
Articles by Olayinka Oluwafemi Asala
Articles by Ahmed Abdulkadir Abdulkadir Gamawa
Articles by Nanven Abraham Maurice
Articles by Anvou Jambol
Articles by Mohammed Bashir Bolajoko
Articles by Nneka Chineze Chima
Articles by Victoria Isioma Ifende
Articles by Yiltawe Simwal Wungak
Articles by Timothy Yusufu Woma
Articles by Pam Dachung Luka
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Adedeji AJ, Adole JA, Asala OO, AAAG, Maurice NA, Jambol A, Bolajoko MB, Chima NC, Ifende VI, Wungak YS, TYW, Luka PD, . A survey of contagious ecthyma and molecular characterization of Orf virus in sheep and goats in Nigeria (2014-2016). Open Vet J. 2022; 12(4): 551-561. doi:10.5455/OVJ.2022.v12.i4.18

Web Style

Adedeji AJ, Adole JA, Asala OO, AAAG, Maurice NA, Jambol A, Bolajoko MB, Chima NC, Ifende VI, Wungak YS, TYW, Luka PD, . A survey of contagious ecthyma and molecular characterization of Orf virus in sheep and goats in Nigeria (2014-2016). https://www.openveterinaryjournal.com/?mno=128469 [Access: December 07, 2024]. doi:10.5455/OVJ.2022.v12.i4.18

AMA (American Medical Association) Style

Adedeji AJ, Adole JA, Asala OO, AAAG, Maurice NA, Jambol A, Bolajoko MB, Chima NC, Ifende VI, Wungak YS, TYW, Luka PD, . A survey of contagious ecthyma and molecular characterization of Orf virus in sheep and goats in Nigeria (2014-2016). Open Vet J. 2022; 12(4): 551-561. doi:10.5455/OVJ.2022.v12.i4.18


Vancouver/ICMJE Style

Adedeji AJ, Adole JA, Asala OO, AAAG, Maurice NA, Jambol A, Bolajoko MB, Chima NC, Ifende VI, Wungak YS, TYW, Luka PD, . A survey of contagious ecthyma and molecular characterization of Orf virus in sheep and goats in Nigeria (2014-2016). Open Vet J. (2022), [cited December 07, 2024]; 12(4): 551-561. doi:10.5455/OVJ.2022.v12.i4.18


Harvard Style

Adedeji, A. J., Adole, J. A., Asala, O. O., , A. A. A. G., Maurice, N. A., Jambol, A., Bolajoko, M. B., Chima, N. C., Ifende, V. I., Wungak, Y. S., , T. Y. W., Luka, P. D. & (2022) A survey of contagious ecthyma and molecular characterization of Orf virus in sheep and goats in Nigeria (2014-2016). Open Vet J, 12 (4), 551-561. doi:10.5455/OVJ.2022.v12.i4.18


Turabian Style

Adedeji, Adeyinka Jeremy, Jolly Amoche Adole, Olayinka Oluwafemi Asala, Ahmed Abdulkadir Abdulkadir Gamawa, Nanven Abraham Maurice, Anvou Jambol, Mohammed Bashir Bolajoko, Nneka Chineze Chima, Victoria Isioma Ifende, Yiltawe Simwal Wungak, Timothy Yusufu Woma, Pam Dachung Luka, and . 2022. A survey of contagious ecthyma and molecular characterization of Orf virus in sheep and goats in Nigeria (2014-2016). Open Veterinary Journal, 12 (4), 551-561. doi:10.5455/OVJ.2022.v12.i4.18


Chicago Style

Adedeji, Adeyinka Jeremy, Jolly Amoche Adole, Olayinka Oluwafemi Asala, Ahmed Abdulkadir Abdulkadir Gamawa, Nanven Abraham Maurice, Anvou Jambol, Mohammed Bashir Bolajoko, Nneka Chineze Chima, Victoria Isioma Ifende, Yiltawe Simwal Wungak, Timothy Yusufu Woma, Pam Dachung Luka, and . "A survey of contagious ecthyma and molecular characterization of Orf virus in sheep and goats in Nigeria (2014-2016)." Open Veterinary Journal 12 (2022), 551-561. doi:10.5455/OVJ.2022.v12.i4.18


MLA (The Modern Language Association) Style

Adedeji, Adeyinka Jeremy, Jolly Amoche Adole, Olayinka Oluwafemi Asala, Ahmed Abdulkadir Abdulkadir Gamawa, Nanven Abraham Maurice, Anvou Jambol, Mohammed Bashir Bolajoko, Nneka Chineze Chima, Victoria Isioma Ifende, Yiltawe Simwal Wungak, Timothy Yusufu Woma, Pam Dachung Luka, and . "A survey of contagious ecthyma and molecular characterization of Orf virus in sheep and goats in Nigeria (2014-2016)." Open Veterinary Journal 12.4 (2022), 551-561. Print. doi:10.5455/OVJ.2022.v12.i4.18


APA (American Psychological Association) Style

Adedeji, A. J., Adole, J. A., Asala, O. O., , A. A. A. G., Maurice, N. A., Jambol, A., Bolajoko, M. B., Chima, N. C., Ifende, V. I., Wungak, Y. S., , T. Y. W., Luka, P. D. & (2022) A survey of contagious ecthyma and molecular characterization of Orf virus in sheep and goats in Nigeria (2014-2016). Open Veterinary Journal, 12 (4), 551-561. doi:10.5455/OVJ.2022.v12.i4.18


Author LoginReviewer LoginAbout PublisherPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyTerms of UseLicense Information

About Open Veterinary Journal

Open Veterinary Journal provides a fast track coupled with high quality peer review process for original research articles, review articles, short communi ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information

All correspondence should be addressed to:

Prof. Ibrahim Eldaghayes: Owner, Founder and Editor-in-Chief

Open Veterinary Journal


Faculty of Veterinary Medicine, University of Tripoli

P.O. Box 13662, Tripoli, Libya

and


Eldaghayes Publisher

www.eldagpublisher.com 

Email: ibrahim.eldaghayes@vetmed.edu.ly