E-ISSN 2218-6050 | ISSN 2226-4485
 

Review Article


MALIGNANT RENAL SCHWANNOMA IN A CAT: A case study

Monier Sharif, Adel Mohamed, Manfred Reinacher.


Cited By:3

Abstract
We present a case of a 9-year-old male European shorthair cat with rapidly enlarging mass at the left kidney doubted to be malignant. The purpose of this study is to present the clinical, radiological and pathological findings of a primary renal tumor in the cat. Grossly, the mass mostly encapsulated the kidney. Histologically, excisional biopsy showed worrying histological features. A sarcoma-like tumor composed mainly of neoplastic spindle-shaped cells. Neoplastic nodules of aggregations of fusiform cells arranged in multidirectional bundles.
Immunohistochemically, several immunohistochemical satins (melan-A, S-100, vimentin, actin, desmin, cytokeratin, neurofilament, melan-A, NSE, synaptophysin, chromogranin, Glial Fibrillary Acidic Protein GFAP, Collagen IV and CD99) were used to differentially diagnose the mass. The stained neoplastic sections positively tested to S-100, but negative to the other aforementioned immunohistochemical stains. Immunohistochemistry with S-100 antibody staining showed an unusually strong positive reaction throughout the tumor cells.
Based on our comparative diagnosis relative to other tumors, in addition to the progressive clinical signs, histopathological and immunohistochemical results, this case was presumptively diagnosis as a malignant schwannoma.
According to our investigation of the relevant literature, this study of malignant renal Schwannoma (malignant peripheral nerve sheath tumor) is a highly rare case not previously characterized in a cat.

Key words: Schwannoma Immunohistochemistry


 
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Pubmed Style

Monier Sharif, Adel Mohamed, Manfred Reinacher. MALIGNANT RENAL SCHWANNOMA IN A CAT: A case study. Open Vet J. 2017; 7(3): 214-220. doi:10.4314/ovj.v7i3.3


Web Style

Monier Sharif, Adel Mohamed, Manfred Reinacher. MALIGNANT RENAL SCHWANNOMA IN A CAT: A case study. https://www.openveterinaryjournal.com/?mno=251720 [Access: February 27, 2024]. doi:10.4314/ovj.v7i3.3


AMA (American Medical Association) Style

Monier Sharif, Adel Mohamed, Manfred Reinacher. MALIGNANT RENAL SCHWANNOMA IN A CAT: A case study. Open Vet J. 2017; 7(3): 214-220. doi:10.4314/ovj.v7i3.3



Vancouver/ICMJE Style

Monier Sharif, Adel Mohamed, Manfred Reinacher. MALIGNANT RENAL SCHWANNOMA IN A CAT: A case study. Open Vet J. (2017), [cited February 27, 2024]; 7(3): 214-220. doi:10.4314/ovj.v7i3.3



Harvard Style

Monier Sharif, Adel Mohamed, Manfred Reinacher (2017) MALIGNANT RENAL SCHWANNOMA IN A CAT: A case study. Open Vet J, 7 (3), 214-220. doi:10.4314/ovj.v7i3.3



Turabian Style

Monier Sharif, Adel Mohamed, Manfred Reinacher. 2017. MALIGNANT RENAL SCHWANNOMA IN A CAT: A case study. Open Veterinary Journal, 7 (3), 214-220. doi:10.4314/ovj.v7i3.3



Chicago Style

Monier Sharif, Adel Mohamed, Manfred Reinacher. "MALIGNANT RENAL SCHWANNOMA IN A CAT: A case study." Open Veterinary Journal 7 (2017), 214-220. doi:10.4314/ovj.v7i3.3



MLA (The Modern Language Association) Style

Monier Sharif, Adel Mohamed, Manfred Reinacher. "MALIGNANT RENAL SCHWANNOMA IN A CAT: A case study." Open Veterinary Journal 7.3 (2017), 214-220. Print. doi:10.4314/ovj.v7i3.3



APA (American Psychological Association) Style

Monier Sharif, Adel Mohamed, Manfred Reinacher (2017) MALIGNANT RENAL SCHWANNOMA IN A CAT: A case study. Open Veterinary Journal, 7 (3), 214-220. doi:10.4314/ovj.v7i3.3