E-ISSN 2218-6050 | ISSN 2226-4485
 

Case Report


Malignant pilomatricoma in a dog with local and distant metastases treated with chemotherapy and bisphosphonates

Elisabetta Treggiari, James W Elliott.


Cited By:6

Abstract
A ten-year-old male neutered cross breed dog presented for evaluation of a mass associated with the left scapular bone, identified as a carcinoma. The dog had a malignant pilomatricoma removed from the left lateral thigh 6 months earlier.
Histopathology review of the cutaneous and scapular mass identified the same tumour type, confirming metastatic disease; additional metastases to the inguinal lymph node, liver and lungs were identified. Chemotherapy resulted in partial responses/stable disease of very short duration. Bisphosphonates were administered due to lack of a measurable response and worsening of the associated lameness. The patient ultimately developed a symptomatic vertebral metastasis and was euthanased. He survived 255 days since medical treatment was started and 455 days since surgical removal of the primary tumour. This case report suggests that medical treatment with the addition of analgesia may be able to palliate clinical signs and possibly extend survival in dogs with metastatic epithelial cancer.

Key words: Malignant pilomatricoma, dog, metastases, chemotherapy, bisphosphonates


 
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How to Cite this Article
Pubmed Style

Elisabetta Treggiari, James W Elliott. Malignant pilomatricoma in a dog with local and distant metastases treated with chemotherapy and bisphosphonates. Open Vet J. 2017; 7(3): 208-213. doi:10.4314/ovj.v7i3.2


Web Style

Elisabetta Treggiari, James W Elliott. Malignant pilomatricoma in a dog with local and distant metastases treated with chemotherapy and bisphosphonates. https://www.openveterinaryjournal.com/?mno=254972 [Access: October 10, 2024]. doi:10.4314/ovj.v7i3.2


AMA (American Medical Association) Style

Elisabetta Treggiari, James W Elliott. Malignant pilomatricoma in a dog with local and distant metastases treated with chemotherapy and bisphosphonates. Open Vet J. 2017; 7(3): 208-213. doi:10.4314/ovj.v7i3.2



Vancouver/ICMJE Style

Elisabetta Treggiari, James W Elliott. Malignant pilomatricoma in a dog with local and distant metastases treated with chemotherapy and bisphosphonates. Open Vet J. (2017), [cited October 10, 2024]; 7(3): 208-213. doi:10.4314/ovj.v7i3.2



Harvard Style

Elisabetta Treggiari, James W Elliott (2017) Malignant pilomatricoma in a dog with local and distant metastases treated with chemotherapy and bisphosphonates. Open Vet J, 7 (3), 208-213. doi:10.4314/ovj.v7i3.2



Turabian Style

Elisabetta Treggiari, James W Elliott. 2017. Malignant pilomatricoma in a dog with local and distant metastases treated with chemotherapy and bisphosphonates. Open Veterinary Journal, 7 (3), 208-213. doi:10.4314/ovj.v7i3.2



Chicago Style

Elisabetta Treggiari, James W Elliott. "Malignant pilomatricoma in a dog with local and distant metastases treated with chemotherapy and bisphosphonates." Open Veterinary Journal 7 (2017), 208-213. doi:10.4314/ovj.v7i3.2



MLA (The Modern Language Association) Style

Elisabetta Treggiari, James W Elliott. "Malignant pilomatricoma in a dog with local and distant metastases treated with chemotherapy and bisphosphonates." Open Veterinary Journal 7.3 (2017), 208-213. Print. doi:10.4314/ovj.v7i3.2



APA (American Psychological Association) Style

Elisabetta Treggiari, James W Elliott (2017) Malignant pilomatricoma in a dog with local and distant metastases treated with chemotherapy and bisphosphonates. Open Veterinary Journal, 7 (3), 208-213. doi:10.4314/ovj.v7i3.2