E-ISSN 2218-6050 | ISSN 2226-4485
 
2024, Vol: 14, Issue: 4
14 / 4Current Issue ArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles
Required files to be uploaded

OVJ Manuscript Submission Form

Research Article


Impact of Sel-Plex® dietary supplementation on growth performance, physiological response, oxidative status, and immunity linked gene expression in Nile tilapia (Oreochromis niloticus) fingerlings challenged with Aeromonas hydrophila

Eman M. Moustafa, Mostafa Shukry, Mohamed M. Zayed, Foad A. Farrag, Wesam E. Abd El-Aziz, Amira A. Omar.


Abstract
Background:
Organic selenium (Sel-Plex®) supplementation holds a considerable promise for improving the effectiveness of fish production.
Aim:
This experiment was accomplished to judge the potential benefits of Sel-Plex® nutritional additive on growth outcomes, physiological response, oxidative status, and immunity-linked gene expression in Nile tilapia (Oreochromis niloticus) fingerlings exposed to bacterial infection with Aeromonas hydrophila.
Methods:
Utilizing a basal diet of 30% protein, four experimental diets were prepared, each of which contained Sel-Plex® at concentrations of 0.0, 0.5, 1, and 2 mg/kg, respectively. Three replicates of 20 fish/treatment were used using 240 healthy Nile tilapia fingerlings. Fish were placed in twelve glass aquariums and separated into four groups at random. For the entire span of 8 weeks, diets were admitted to fish at a 3% rate of fish biomass/aquarium. After the feeding trial, pathogenic Aeromonas hydrophila was intraperitoneally injected into fish of each treatment, and fish were observed for fifteen days to track the survival rate after the challenge.
Results:
Growth performance, physiological response, immunological parameters (Phagocytic activity, Phagocytic index, and Lysozyme), and antioxidant parameters (Catalase, Superoxide dismutase, Malondialdehyde, and Glutathione Peroxidase) were noticeably improved in Sel-Plex® treated groups. Moreover, Sel-Plex® increased gene expression linked with the immune system in the liver (TNF-α, and IL-1β), to growth (IGF-1, and GHr), and antioxidants (SOD, and GSH-Px). Under pathogen-challenge conditions, the employed dietary Sel-Plex® supplementation could successfully lower fish oxidative stress, offering a potential preventive additive for Nile tilapia instead of antibiotics. On the other hand, Sel-Plex® significantly enhanced each of three intestinal morphological measurements (villus width, villus length, and crypt depth), demonstrating the greatest influence on the improvement of intestinal structure overall. In the Nile tilapia control group, the infection with A. hydrophila caused noticeable degenerative alterations in the gut, hepatopancreas, spleen, and posterior kidney. The severity of the lesion was significantly reduced and significantly improved with higher Sel-Plex® concentrations. Sel-Plex® supplemented groups had 100% survival rates among the A. hydrophila-challenged groups.
Conclusion:
It could be advised to enrich the diets of Nile tilapia fingerlings with 1-2 mg.kg−1 of Sel-Plex® to enhance growth rate, physiological response, immunological reaction, and intestinal absorptive capacity.

Key words: Aeromonas hydrophila, Immune-related gene expression, Nile tilapia, Organic selenium, Oxidative status


 
ARTICLE TOOLS
Abstract
PDF Fulltext
HTML Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Eman M. Moustafa
Articles by Mostafa Shukry
Articles by Mohamed M. Zayed
Articles by Foad A. Farrag
Articles by Wesam E. Abd El-Aziz
Articles by Amira A. Omar
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Moustafa EM, Shukry M, Zayed MM, Farrag FA, El-Aziz WEA, Omar AA. Impact of Sel-Plex® dietary supplementation on growth performance, physiological response, oxidative status, and immunity linked gene expression in Nile tilapia (Oreochromis niloticus) fingerlings challenged with Aeromonas hydrophila. Open Vet J. 2024; 14((1) (Zagazig Veterinary Conference)): 70 -89 . doi:10.5455/OVJ.2024.v14.i1.8

Web Style

Moustafa EM, Shukry M, Zayed MM, Farrag FA, El-Aziz WEA, Omar AA. Impact of Sel-Plex® dietary supplementation on growth performance, physiological response, oxidative status, and immunity linked gene expression in Nile tilapia (Oreochromis niloticus) fingerlings challenged with Aeromonas hydrophila. https://www.openveterinaryjournal.com/?mno=175107 [Access: May 03, 2024]. doi:10.5455/OVJ.2024.v14.i1.8

AMA (American Medical Association) Style

Moustafa EM, Shukry M, Zayed MM, Farrag FA, El-Aziz WEA, Omar AA. Impact of Sel-Plex® dietary supplementation on growth performance, physiological response, oxidative status, and immunity linked gene expression in Nile tilapia (Oreochromis niloticus) fingerlings challenged with Aeromonas hydrophila. Open Vet J. 2024; 14((1) (Zagazig Veterinary Conference)): 70 -89 . doi:10.5455/OVJ.2024.v14.i1.8


Vancouver/ICMJE Style

Moustafa EM, Shukry M, Zayed MM, Farrag FA, El-Aziz WEA, Omar AA. Impact of Sel-Plex® dietary supplementation on growth performance, physiological response, oxidative status, and immunity linked gene expression in Nile tilapia (Oreochromis niloticus) fingerlings challenged with Aeromonas hydrophila. Open Vet J. (2024), [cited May 03, 2024]; 14((1) (Zagazig Veterinary Conference)): 70 -89 . doi:10.5455/OVJ.2024.v14.i1.8


Harvard Style

Moustafa, E. M., Shukry, . M., Zayed, . M. M., Farrag, . F. A., El-Aziz, . W. E. A. & Omar, . A. A. (2024) Impact of Sel-Plex® dietary supplementation on growth performance, physiological response, oxidative status, and immunity linked gene expression in Nile tilapia (Oreochromis niloticus) fingerlings challenged with Aeromonas hydrophila. Open Vet J, 14 ((1) (Zagazig Veterinary Conference)), 70 -89 . doi:10.5455/OVJ.2024.v14.i1.8


Turabian Style

Moustafa, Eman M., Mostafa Shukry, Mohamed M. Zayed, Foad A. Farrag, Wesam E. Abd El-Aziz, and Amira A. Omar. 2024. Impact of Sel-Plex® dietary supplementation on growth performance, physiological response, oxidative status, and immunity linked gene expression in Nile tilapia (Oreochromis niloticus) fingerlings challenged with Aeromonas hydrophila. Open Veterinary Journal, 14 ((1) (Zagazig Veterinary Conference)), 70 -89 . doi:10.5455/OVJ.2024.v14.i1.8


Chicago Style

Moustafa, Eman M., Mostafa Shukry, Mohamed M. Zayed, Foad A. Farrag, Wesam E. Abd El-Aziz, and Amira A. Omar. "Impact of Sel-Plex® dietary supplementation on growth performance, physiological response, oxidative status, and immunity linked gene expression in Nile tilapia (Oreochromis niloticus) fingerlings challenged with Aeromonas hydrophila." Open Veterinary Journal 14 (2024), 70 -89 . doi:10.5455/OVJ.2024.v14.i1.8


MLA (The Modern Language Association) Style

Moustafa, Eman M., Mostafa Shukry, Mohamed M. Zayed, Foad A. Farrag, Wesam E. Abd El-Aziz, and Amira A. Omar. "Impact of Sel-Plex® dietary supplementation on growth performance, physiological response, oxidative status, and immunity linked gene expression in Nile tilapia (Oreochromis niloticus) fingerlings challenged with Aeromonas hydrophila." Open Veterinary Journal 14.(1) (Zagazig Veterinary Conference) (2024), 70 -89 . Print. doi:10.5455/OVJ.2024.v14.i1.8


APA (American Psychological Association) Style

Moustafa, E. M., Shukry, . M., Zayed, . M. M., Farrag, . F. A., El-Aziz, . W. E. A. & Omar, . A. A. (2024) Impact of Sel-Plex® dietary supplementation on growth performance, physiological response, oxidative status, and immunity linked gene expression in Nile tilapia (Oreochromis niloticus) fingerlings challenged with Aeromonas hydrophila. Open Veterinary Journal, 14 ((1) (Zagazig Veterinary Conference)), 70 -89 . doi:10.5455/OVJ.2024.v14.i1.8


Author LoginReviewer LoginAbout PublisherPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyTerms of UseLicense Information

About Open Veterinary Journal

Open Veterinary Journal provides a fast track coupled with high quality peer review process for original research articles, review articles, short communi ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information

All correspondence should be addressed to:

Prof. Ibrahim Eldaghayes: Owner, Founder and Editor-in-Chief

Open Veterinary Journal, Faculty of Veterinary Medicine, University of Tripoli

P.O. Box 13662, Tripoli, Libya


Email: ibrahim.eldaghayes@vetmed.edu.ly