E-ISSN 2218-6050 | ISSN 2226-4485
 
2024, Vol: 14, Issue: 11
14 / 11Current Issue ArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles
Required files to be uploaded

OVJ Manuscript Submission Form

Original Article


CUSHING’S SYNDROME – AN EPIDEMIOLOGICAL STUDY BASED ON A CANINE POPULATION OF 21,281 DOGS

Gaia Carotenuto, Eleonora Malerba, Costanza Dolfini, Francesca Brugnoli, Pasquale Giannuzzi, Giovanni Semprini, Paolo Tosolini, Federico Fracassi.


Cited By:64

Abstract
The epidemiological characteristics of Cushing’s syndrome (CS) were derived from 21,281 client-owned dogs selected from 4 private veterinary clinics and 1 university reference centre for endocrinology. The odds ratio (OR) method was employed to investigate the risk of developing CS related to breed, gender and sexual status.
The estimated prevalence of CS in the 4 private clinics was 0.20% (95% CI, 0.13–0.27) and was significantly different compared to the university reference centre (1.46%; 95%CI, 1.12–1.80). Sex, breed and age resulted in risk factors for CS. Mean (±SD) age for dogs with CS was 9.8 (±2.5) years. Females had higher risk for CS compared to males (OR 1.85; 95%CI, 1.24–2.75); neutered dogs had higher risk than intact dogs (OR 2.54; 95%CI, 1.72–3.73); and neutered females had higher risk compared to intact females (OR 2.61; 95%CI, 1.54–4.42). Using the mixed breed dogs as a control population (OR=1), the risk of developing CS was significantly higher in the standard schnauzer (OR 58.1; p<0.0001) and fox terrier (OR 20.33; p<0.0001).
With regard to CS, this study identified an overall prevalence of 0.20%. The data support the existence of sex predisposition, with the highest risk for neutered females.

Key words: Hypercortisolism, Hyperadrenocorticism, PDH, cortisol,


 
ARTICLE TOOLS
Abstract
PDF Fulltext
HTML Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Gaia Carotenuto
Articles by Eleonora Malerba
Articles by Costanza Dolfini
Articles by Francesca Brugnoli
Articles by Pasquale Giannuzzi
Articles by Giovanni Semprini
Articles by Paolo Tosolini
Articles by Federico Fracassi
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Carotenuto G, Malerba E, Dolfini C, Brugnoli F, Giannuzzi P, Semprini G, Tosolini P, Fracassi F, . CUSHING’S SYNDROME – AN EPIDEMIOLOGICAL STUDY BASED ON A CANINE POPULATION OF 21,281 DOGS . Open Vet J. 2019; 9(1): 27-32. doi:10.4314/ovj.v9i1.5

Web Style

Carotenuto G, Malerba E, Dolfini C, Brugnoli F, Giannuzzi P, Semprini G, Tosolini P, Fracassi F, . CUSHING’S SYNDROME – AN EPIDEMIOLOGICAL STUDY BASED ON A CANINE POPULATION OF 21,281 DOGS . https://www.openveterinaryjournal.com/?mno=5068 [Access: December 07, 2024]. doi:10.4314/ovj.v9i1.5

AMA (American Medical Association) Style

Carotenuto G, Malerba E, Dolfini C, Brugnoli F, Giannuzzi P, Semprini G, Tosolini P, Fracassi F, . CUSHING’S SYNDROME – AN EPIDEMIOLOGICAL STUDY BASED ON A CANINE POPULATION OF 21,281 DOGS . Open Vet J. 2019; 9(1): 27-32. doi:10.4314/ovj.v9i1.5


Vancouver/ICMJE Style

Carotenuto G, Malerba E, Dolfini C, Brugnoli F, Giannuzzi P, Semprini G, Tosolini P, Fracassi F, . CUSHING’S SYNDROME – AN EPIDEMIOLOGICAL STUDY BASED ON A CANINE POPULATION OF 21,281 DOGS . Open Vet J. (2019), [cited December 07, 2024]; 9(1): 27-32. doi:10.4314/ovj.v9i1.5


Harvard Style

Carotenuto, G. ., Malerba, E. ., Dolfini, C. ., Brugnoli, F. ., Giannuzzi, P. ., Semprini, G. ., Tosolini, P. ., Fracassi, F. . & (2019) CUSHING’S SYNDROME – AN EPIDEMIOLOGICAL STUDY BASED ON A CANINE POPULATION OF 21,281 DOGS . Open Vet J, 9 (1), 27-32. doi:10.4314/ovj.v9i1.5


Turabian Style

Carotenuto, Gaia , Eleonora Malerba, Costanza Dolfini, Francesca Brugnoli, Pasquale Giannuzzi, Giovanni Semprini, Paolo Tosolini, Federico Fracassi, and . 2019. CUSHING’S SYNDROME – AN EPIDEMIOLOGICAL STUDY BASED ON A CANINE POPULATION OF 21,281 DOGS . Open Veterinary Journal, 9 (1), 27-32. doi:10.4314/ovj.v9i1.5


Chicago Style

Carotenuto, Gaia , Eleonora Malerba, Costanza Dolfini, Francesca Brugnoli, Pasquale Giannuzzi, Giovanni Semprini, Paolo Tosolini, Federico Fracassi, and . "CUSHING’S SYNDROME – AN EPIDEMIOLOGICAL STUDY BASED ON A CANINE POPULATION OF 21,281 DOGS ." Open Veterinary Journal 9 (2019), 27-32. doi:10.4314/ovj.v9i1.5


MLA (The Modern Language Association) Style

Carotenuto, Gaia , Eleonora Malerba, Costanza Dolfini, Francesca Brugnoli, Pasquale Giannuzzi, Giovanni Semprini, Paolo Tosolini, Federico Fracassi, and . "CUSHING’S SYNDROME – AN EPIDEMIOLOGICAL STUDY BASED ON A CANINE POPULATION OF 21,281 DOGS ." Open Veterinary Journal 9.1 (2019), 27-32. Print. doi:10.4314/ovj.v9i1.5


APA (American Psychological Association) Style

Carotenuto, G. ., Malerba, E. ., Dolfini, C. ., Brugnoli, F. ., Giannuzzi, P. ., Semprini, G. ., Tosolini, P. ., Fracassi, F. . & (2019) CUSHING’S SYNDROME – AN EPIDEMIOLOGICAL STUDY BASED ON A CANINE POPULATION OF 21,281 DOGS . Open Veterinary Journal, 9 (1), 27-32. doi:10.4314/ovj.v9i1.5


Author LoginReviewer LoginAbout PublisherPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyTerms of UseLicense Information

About Open Veterinary Journal

Open Veterinary Journal provides a fast track coupled with high quality peer review process for original research articles, review articles, short communi ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information

All correspondence should be addressed to:

Prof. Ibrahim Eldaghayes: Owner, Founder and Editor-in-Chief

Open Veterinary Journal


Faculty of Veterinary Medicine, University of Tripoli

P.O. Box 13662, Tripoli, Libya

and


Eldaghayes Publisher

www.eldagpublisher.com 

Email: ibrahim.eldaghayes@vetmed.edu.ly