E-ISSN 2218-6050 | ISSN 2226-4485
 
2024, Vol: 14, Issue: 3
14 / 3Current Issue ArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles
Required files to be uploaded

OVJ Manuscript Submission Form

Original Article


Insecticidal Efficacy and Safety of Phoxim and Influence on Hematological, Biochemical, and Antioxidant Profiles in German Shepherd Dogs

Mamdouh M. El-Maghraby, Ahmed E. Mahmoud, Dina A. Abdelkhalek, Nahla H. Sallam, Abdelfatah N. Aly, Aliaa A. Abd-Elaziz, Essam S. Soliman.


Abstract
Background: Dogs’ health and welfare enhancement can be achieved using some prophylactics and immunization go with strict hygienic and optimum biosecurity measures.
Aim: Exploration of the insecticidal action of Phoxim® for combating Rhipicephalus sanguineus infestation in dogs and its prophylactic influences on the blood indices, biochemistry, antioxidant enzymes, and cortisol hormone in healthy and infested dogs.
Methods: Twenty German Shepherd male dogs at one year old and 44.0 kg were divided randomly into four groups of five dogs in four separate Kennels with optimum biosecurity measures. The 1st group (G1) was artificially infested with R. sanguineus and treated with Phoxim®, the 2nd (G2) was non-infested and treated with Phoxim®, the 3rd (G3) was infested with R. sanguineus and not treated (positive control), and the 4th (G4) was accounted as negative control (non-infested and non-treated). A total of 160 (80 whole blood and 80 sera) samples were collected.
Results: Parasitological examination revealed prominent characteristic features of R. sanguineus such as a distinct anal groove, the basis capitulum is hexagonal and lateral, the palpi are short, the second segment of the palpi as long as wide and not produced laterally, and the spiracular plate is comma-shaped and consists of stigma, peritreme, and tail. The results conveyed highly significant (p < 0.01) enhancement in erythrocytes, leukocytes, hematohiston, hematocrit, hemoglobin centering, granulocytes, alanine aminotransferase, random blood sugars, triglycerides, and total cholesterol, and highly significant (p < 0.01) declines of all measured antioxidant enzymes in treated non-infested dogs.
Conclusion: Phoxim® proved efficient insecticidal activity with optimum safety and can be brought into play in the prophylactic biosecurity measures installed to eradicate external parasitism in dogs.

Key words: Biosecurity, Dogs, Phoxim®, Prophylactic Efficacy, Rhipicephalus sanguineus.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
HTML Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Mamdouh M. El-Maghraby
Articles by Ahmed E. Mahmoud
Articles by Dina A. Abdelkhalek
Articles by Nahla H. Sallam
Articles by Abdelfatah N. Aly
Articles by Aliaa A. Abd-Elaziz
Articles by Essam S. Soliman
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

El-Maghraby MM, Mahmoud AE, Abdelkhalek DA, Sallam NH, Aly AN, Abd-Elaziz AA, Soliman ES. Insecticidal Efficacy and Safety of Phoxim and Influence on Hematological, Biochemical, and Antioxidant Profiles in German Shepherd Dogs. Open Vet J. 2022; 12(6): 888-902. doi:10.5455/OVJ.2022.v12.i6.15

Web Style

El-Maghraby MM, Mahmoud AE, Abdelkhalek DA, Sallam NH, Aly AN, Abd-Elaziz AA, Soliman ES. Insecticidal Efficacy and Safety of Phoxim and Influence on Hematological, Biochemical, and Antioxidant Profiles in German Shepherd Dogs. https://www.openveterinaryjournal.com/?mno=90861 [Access: April 21, 2024]. doi:10.5455/OVJ.2022.v12.i6.15

AMA (American Medical Association) Style

El-Maghraby MM, Mahmoud AE, Abdelkhalek DA, Sallam NH, Aly AN, Abd-Elaziz AA, Soliman ES. Insecticidal Efficacy and Safety of Phoxim and Influence on Hematological, Biochemical, and Antioxidant Profiles in German Shepherd Dogs. Open Vet J. 2022; 12(6): 888-902. doi:10.5455/OVJ.2022.v12.i6.15


Vancouver/ICMJE Style

El-Maghraby MM, Mahmoud AE, Abdelkhalek DA, Sallam NH, Aly AN, Abd-Elaziz AA, Soliman ES. Insecticidal Efficacy and Safety of Phoxim and Influence on Hematological, Biochemical, and Antioxidant Profiles in German Shepherd Dogs. Open Vet J. (2022), [cited April 21, 2024]; 12(6): 888-902. doi:10.5455/OVJ.2022.v12.i6.15


Harvard Style

El-Maghraby, M. M., Mahmoud, . A. E., Abdelkhalek, . D. A., Sallam, . N. H., Aly, . A. N., Abd-Elaziz, . A. A. & Soliman, . E. S. (2022) Insecticidal Efficacy and Safety of Phoxim and Influence on Hematological, Biochemical, and Antioxidant Profiles in German Shepherd Dogs. Open Vet J, 12 (6), 888-902. doi:10.5455/OVJ.2022.v12.i6.15


Turabian Style

El-Maghraby, Mamdouh M., Ahmed E. Mahmoud, Dina A. Abdelkhalek, Nahla H. Sallam, Abdelfatah N. Aly, Aliaa A. Abd-Elaziz, and Essam S. Soliman. 2022. Insecticidal Efficacy and Safety of Phoxim and Influence on Hematological, Biochemical, and Antioxidant Profiles in German Shepherd Dogs. Open Veterinary Journal, 12 (6), 888-902. doi:10.5455/OVJ.2022.v12.i6.15


Chicago Style

El-Maghraby, Mamdouh M., Ahmed E. Mahmoud, Dina A. Abdelkhalek, Nahla H. Sallam, Abdelfatah N. Aly, Aliaa A. Abd-Elaziz, and Essam S. Soliman. "Insecticidal Efficacy and Safety of Phoxim and Influence on Hematological, Biochemical, and Antioxidant Profiles in German Shepherd Dogs." Open Veterinary Journal 12 (2022), 888-902. doi:10.5455/OVJ.2022.v12.i6.15


MLA (The Modern Language Association) Style

El-Maghraby, Mamdouh M., Ahmed E. Mahmoud, Dina A. Abdelkhalek, Nahla H. Sallam, Abdelfatah N. Aly, Aliaa A. Abd-Elaziz, and Essam S. Soliman. "Insecticidal Efficacy and Safety of Phoxim and Influence on Hematological, Biochemical, and Antioxidant Profiles in German Shepherd Dogs." Open Veterinary Journal 12.6 (2022), 888-902. Print. doi:10.5455/OVJ.2022.v12.i6.15


APA (American Psychological Association) Style

El-Maghraby, M. M., Mahmoud, . A. E., Abdelkhalek, . D. A., Sallam, . N. H., Aly, . A. N., Abd-Elaziz, . A. A. & Soliman, . E. S. (2022) Insecticidal Efficacy and Safety of Phoxim and Influence on Hematological, Biochemical, and Antioxidant Profiles in German Shepherd Dogs. Open Veterinary Journal, 12 (6), 888-902. doi:10.5455/OVJ.2022.v12.i6.15


Author LoginReviewer LoginAbout PublisherPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyTerms of UseLicense Information

About Open Veterinary Journal

Open Veterinary Journal provides a fast track coupled with high quality peer review process for original research articles, review articles, short communi ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information

All correspondence should be addressed to:

Prof. Ibrahim Eldaghayes: Owner, Founder and Editor-in-Chief

Open Veterinary Journal, Faculty of Veterinary Medicine, University of Tripoli

P.O. Box 13662, Tripoli, Libya


Email: ibrahim.eldaghayes@vetmed.edu.ly